Acute Myocardial Infarction With Nonobstructive Coronary Arteries Across Endocrine Disorders: A Case Series.

JCEM case reports Pub Date : 2025-02-10 eCollection Date: 2025-03-01 DOI:10.1210/jcemcr/luaf024
Ayan Roy, Deepika Patel, Chandhana Merugu, Sadishkumar Kamalanathan, Jayaprakash Sahoo, Dukhabandhu Naik
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Abstract

The endocrine and cardiology interface is particularly interesting and important. This is a case series of 3 endocrine diseases presenting with acute myocardial infarction without obstructive coronary arterial diseases (MINOCA). The diagnosis was Cushing's disease due to pituitary microadenoma, adrenal pheochromocytoma, and primary hyperaldosteronism due to unilateral adrenal hyperplasia. All patients were managed conservatively and improved considerably following the management of underlying endocrine and cardiovascular diseases. A spectrum of classical endocrine diseases can present with MINOCA, and the underlying diagnosis is often overlooked. Patients without traditional risk factors for MINOCA should undergo hormonal workup to reveal the underlying diagnosis.

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