Acute Myocardial Infarction With Nonobstructive Coronary Arteries Across Endocrine Disorders: A Case Series.

JCEM case reports Pub Date : 2025-02-10 eCollection Date: 2025-03-01 DOI:10.1210/jcemcr/luaf024
Ayan Roy, Deepika Patel, Chandhana Merugu, Sadishkumar Kamalanathan, Jayaprakash Sahoo, Dukhabandhu Naik
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Abstract

The endocrine and cardiology interface is particularly interesting and important. This is a case series of 3 endocrine diseases presenting with acute myocardial infarction without obstructive coronary arterial diseases (MINOCA). The diagnosis was Cushing's disease due to pituitary microadenoma, adrenal pheochromocytoma, and primary hyperaldosteronism due to unilateral adrenal hyperplasia. All patients were managed conservatively and improved considerably following the management of underlying endocrine and cardiovascular diseases. A spectrum of classical endocrine diseases can present with MINOCA, and the underlying diagnosis is often overlooked. Patients without traditional risk factors for MINOCA should undergo hormonal workup to reveal the underlying diagnosis.

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内分泌失调性非阻塞性冠状动脉急性心肌梗死:病例系列。
内分泌和心脏病学的结合尤其有趣和重要。本文报告3例内分泌疾病合并急性心肌梗死,无阻塞性冠状动脉疾病(MINOCA)。诊断为垂体微腺瘤、肾上腺嗜铬细胞瘤及单侧肾上腺增生所致原发性醛固酮增多症所致的库欣病。所有患者均采用保守治疗,并在治疗基础内分泌和心血管疾病后显著改善。MINOCA可表现为一系列经典内分泌疾病,但其潜在诊断常被忽视。没有MINOCA传统危险因素的患者应接受激素检查以揭示潜在的诊断。
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