Mechanotransduction in the Perivascular Adipose Tissue.

IF 7.4 1区 医学 Q1 HEMATOLOGY Arteriosclerosis, Thrombosis, and Vascular Biology Pub Date : 2025-02-13 DOI:10.1161/ATVBAHA.124.321688
Stephanie W Watts, Teresa Krieger-Burke, Rance Nault, G Andres Contreras
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引用次数: 0

Abstract

Perivascular adipose tissue is of compelling interest when considering tissue mechanotransduction. Because of its location around a vessel, perivascular adipose tissue experiences from high (artery) to low (vein) pressures, pressures that are cyclical in nature. With blood pressure change, such as the elevation of pressure in hypertension, the question has been raised as to whether perivascular adipose tissue senses such changes, evidenced by a response that can be genetic, structural, or mechanical in nature. Here, we briefly review the following knowledge and data that support the ability of perivascular adipose tissue to both (mechano)sense and (mechano)respond.

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来源期刊
CiteScore
15.60
自引率
2.30%
发文量
337
审稿时长
2-4 weeks
期刊介绍: The journal "Arteriosclerosis, Thrombosis, and Vascular Biology" (ATVB) is a scientific publication that focuses on the fields of vascular biology, atherosclerosis, and thrombosis. It is a peer-reviewed journal that publishes original research articles, reviews, and other scholarly content related to these areas. The journal is published by the American Heart Association (AHA) and the American Stroke Association (ASA). The journal was published bi-monthly until January 1992, after which it transitioned to a monthly publication schedule. The journal is aimed at a professional audience, including academic cardiologists, vascular biologists, physiologists, pharmacologists and hematologists.
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