Is Posterior Transvaginal Mesh Surgery Using PTFE Mesh ORIHIME Effective and Safe for Advanced Posterior Vaginal Prolapse?

IF 2.2 3区 医学 Q3 UROLOGY & NEPHROLOGY International Journal of Urology Pub Date : 2025-02-13 DOI:10.1111/iju.70008
Kazunobu Yagi, Masami Takeyama, Yukiko Doi, Tomoko Kuwata, Hiromi Kashihara, Chikako Kato
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Abstract

Objectives

To examine the efficacy and safety of posterior tension-free vaginal mesh (TVM-P) surgery using polytetrafluoroethylene (PTFE) mesh (ORIHIME) for advanced posterior vaginal prolapse.

Methods

A retrospective cohort study was conducted involving patients who underwent TVM-P surgery with PTFE mesh for pelvic organ prolapse quantification stage III or IV posterior vaginal prolapse between December 2018 and March 2023. All patients were followed for a minimum of 1 year postoperatively. The primary outcome was the recurrence rate in the operated compartment. Secondary outcomes comprised recurrence in other pelvic compartments, mesh-related complications, and an analysis of risk factors for recurrence.

Results

Seventy-one patients underwent TVM-P surgery during the study period. The recurrence rate in the operated compartment was 4.2%, while the overall recurrence rate was 18.3%. Eleven cases of recurrence occurred within the first year; 13 cases were observed within 3 years postsurgery. Patients who experienced recurrence in other compartments had a significantly higher incidence of preoperative Ba point score ≥ −1 versus the nonrecurrence group. Preoperative Ba point score ≥ −1 was associated with a higher risk of recurrence in other compartments (crude odds ratio: 4.17, 95% confidence interval: 1.03–26.7; adjusted odds ratio: 2.58, 95% confidence interval: 0.56–11.8).

Conclusions

The recurrence rate in the operated compartment following TVM-P surgery for advanced rectoceles or enteroceles was 4.2%. These findings suggest that TVM-P surgery using PTFE mesh may be an effective surgical option for treating severe posterior vaginal pelvic organ prolapse.

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使用聚四氟乙烯网ORIHIME治疗晚期阴道后脱垂有效且安全吗?
目的:探讨聚四氟乙烯(PTFE)补片(ORIHIME)治疗晚期阴道后脱垂的有效性和安全性。方法:回顾性队列研究纳入2018年12月至2023年3月期间接受盆腔器官脱垂量化IV期或IV期阴道后脱垂TVM-P手术的患者。所有患者术后随访至少1年。主要观察指标是手术腔室的复发率。次要结果包括其他骨盆腔室的复发、网状相关并发症和复发危险因素分析。结果:71例患者在研究期间接受了TVM-P手术。手术腔室复发率为4.2%,总复发率为18.3%。1年内复发11例;术后3年内观察13例。其他房室复发的患者术前Ba点评分≥-1的发生率明显高于非复发组。术前Ba点评分≥-1与其他房室复发风险较高相关(粗优势比:4.17,95%可信区间:1.03-26.7;校正优势比:2.58,95%可信区间:0.56-11.8)。结论:TVM-P手术治疗晚期直肠膨出或肠膨出后手术腔室复发率为4.2%。这些发现表明,使用聚四氟乙烯网的TVM-P手术可能是治疗严重阴道后盆腔器官脱垂的有效手术选择。
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来源期刊
International Journal of Urology
International Journal of Urology 医学-泌尿学与肾脏学
CiteScore
4.70
自引率
11.50%
发文量
340
审稿时长
3 months
期刊介绍: International Journal of Urology is the official English language journal of the Japanese Urological Association, publishing articles of scientific excellence in urology. Submissions of papers from all countries are considered for publication. All manuscripts are subject to peer review and are judged on the basis of their contribution of original data and ideas or interpretation.
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