{"title":"Nomogram-based prediction of postoperative complications in patients with hypospadias after perididymis covering.","authors":"Jin-Ming Dong, Ya-Ke Gao, Yan-Dong Yang, Yi-Qun Shi, Li-Na Zhang, Jing Liu, Hai-Jun Zhao, Xiao-Bo Zhao","doi":"10.21037/tp-24-368","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Hypospadias is a prevalent pediatric urological condition. Perididymis covering is often used as a surgical procedure for the treatment of hypospadias. This study aims to investigate the risk factors associated with postoperative complications following perididymis covering in the treatment of hypospadias.</p><p><strong>Methods: </strong>This study involved 204 patients with hypospadias who underwent perididymis cove ring at Tangshan Maternal and Child Health Hospital from May 2018 to May 2024. Patients were followed up for 1 year, with 63 experiencing complications (30.88%) and 141 not experiencing complications (69.12%). Baseline data from both groups were collected and compared. Binary logistic regression analysis was used to analyze the relationship between various factors and postoperative complications. The receiver operating characteristic (ROC) curve and the area under the curve (AUC) were utilized to evaluate the predictive value of the nomogram model for postoperative complications.</p><p><strong>Results: </strong>The complication group had a higher mean age and longer formed urethra lengths compared to the non-complication group. The types of hypospadias were categorized as intermediate, proximal, and those associated with preoperative penile curvature. The AUC for the nomogram model in the prediction of the postoperative complications was 0.909 [95% confidence interval (CI): 0.866-0.952], with a sensitivity of 0.746, a specificity of 0.929, and a Youden's index of 0.675.</p><p><strong>Conclusions: </strong>Age, length of the formed urethra, types of hypospadias, preoperative penile curvature, and surgical methods are significantly associated with postoperative complications following perididymis covering in patients with hypospadias. These indicators can guide the formulation of clinical treatment plans to reduce the incidence of postoperative complications.</p>","PeriodicalId":23294,"journal":{"name":"Translational pediatrics","volume":"14 1","pages":"61-69"},"PeriodicalIF":1.5000,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11811594/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Translational pediatrics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.21037/tp-24-368","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/21 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Hypospadias is a prevalent pediatric urological condition. Perididymis covering is often used as a surgical procedure for the treatment of hypospadias. This study aims to investigate the risk factors associated with postoperative complications following perididymis covering in the treatment of hypospadias.
Methods: This study involved 204 patients with hypospadias who underwent perididymis cove ring at Tangshan Maternal and Child Health Hospital from May 2018 to May 2024. Patients were followed up for 1 year, with 63 experiencing complications (30.88%) and 141 not experiencing complications (69.12%). Baseline data from both groups were collected and compared. Binary logistic regression analysis was used to analyze the relationship between various factors and postoperative complications. The receiver operating characteristic (ROC) curve and the area under the curve (AUC) were utilized to evaluate the predictive value of the nomogram model for postoperative complications.
Results: The complication group had a higher mean age and longer formed urethra lengths compared to the non-complication group. The types of hypospadias were categorized as intermediate, proximal, and those associated with preoperative penile curvature. The AUC for the nomogram model in the prediction of the postoperative complications was 0.909 [95% confidence interval (CI): 0.866-0.952], with a sensitivity of 0.746, a specificity of 0.929, and a Youden's index of 0.675.
Conclusions: Age, length of the formed urethra, types of hypospadias, preoperative penile curvature, and surgical methods are significantly associated with postoperative complications following perididymis covering in patients with hypospadias. These indicators can guide the formulation of clinical treatment plans to reduce the incidence of postoperative complications.