[Expert consensus on clinical practice for pre-pregnancy and prenatal prevention of hereditary hearing loss].

Abstract

Genetic factors are the primary causes of congenital hearing loss, and prevention of hereditary hearing loss is the main breakthrough point in the control and prevention of deafness . The progress in molecular diagnostic technology has effectively improved the diagnostic rate of hereditary hearing loss. Moreover, the findings of population-based molecular epidemiological studies on hearing loss provide theoretical support for the implementation of carrier screening, which aims to identify high-risk families that may give birth to deaf children, and thus lay the foundation for the large-scale prevention of hereditary hearing loss. In view of the lack of unified normative documents on the prevention of hereditary hearing loss in clinical application, a multidisciplinary team of experts consulted the latest evidence-based medicine at home and abroad, and has reached a consensus on the applicable population, strategy, technology, prevention period selection, and clinical process for the pre-pregnancy/prenatal prevention of hereditary hearing loss. The goal is to provide a reference for the clinical standardization implementation of hereditary hearing loss prevention and insight for the research and development of prevention technologies.