Papillary Fibroelastomas: 16-Year Single-Center Experience.

Strahinja Mrvic, Ranko Zdravkovic, Andrej Preveden, Novica Kalinic, Ilija Bjeljac, Aleksandar M Milosavljevic, Mirko Todic
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Abstract

Introduction: Papillary fibroelastoma is a rare primary benign cardiac tumor. The majority of patients are asymptomatic. Complications may result in embolic events, syncope, ventricular arrhythmias, and sudden death. In this study, we report on a series of papillary fibroelastomas documented in our institution.

Methods: Medical history records from period between 2007 and 2022 were reviewed for all the patients diagnosed with cardiac papillary fibroelastomas treated surgically and confirmed histologically. Clinical, tumor, and demographic characteristics, echocardiography findings, and treatment modalities were analyzed.

Results: In a sixteen-year period, 12 cases of papillary fibroelastomas were documented. The percentage of female patients was 83.3%. The average age was 59.0 ± 11.2 years. Average diameter of tumor was 1.2 cm. The aortic valve was the most common origin site, with six cases (50%). In two cases (17%), the mitral valve was involved. There were single cases of tumor (8% each) found on the tricuspid valve, in the left atrium, in the left ventricle, and in the right ventricle. All patients were treated successfully by complete resection.

Conclusion: PFEs are generally small and single tumors. Complete surgical resection of the tumor has a good prognosis and is a safe, efficient, and definitive treatment.

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导读:乳头状纤维母细胞瘤是一种罕见的原发性良性心脏肿瘤:乳头状纤维母细胞瘤是一种罕见的原发性心脏良性肿瘤。大多数患者无症状。并发症可能导致栓塞、晕厥、室性心律失常和猝死。本研究报告了我院记录的一系列乳头状纤维母细胞瘤:方法:回顾 2007 年至 2022 年期间所有经手术治疗和组织学确诊为心脏乳头状纤维母细胞瘤患者的病史记录。分析了临床、肿瘤和人口统计学特征、超声心动图检查结果以及治疗方式:16年间,共记录了12例乳头状纤维母细胞瘤。女性患者占 83.3%。平均年龄为(59.0 ± 11.2)岁。肿瘤平均直径为 1.2 厘米。主动脉瓣是最常见的起源部位,共有六例(50%)。二尖瓣受累的病例有 2 例(17%)。在三尖瓣、左心房、左心室和右心室也发现了肿瘤(各占 8%)。所有患者均通过完全切除术成功治愈:结论:PFE 通常是单发的小肿瘤。结论:PFE 通常是单发的小肿瘤,完全手术切除预后良好,是一种安全、高效、彻底的治疗方法。
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