The Epidemiological Profile of Tuberculosis Patients and Risk Factors for Poor Treatment Outcomes in Sarpang District, Bhutan: A 17 Years Retrospective Study.

IF 0.9 4区医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Asia-Pacific Journal of Public Health Pub Date : 2025-03-01 Epub Date: 2025-02-13 DOI:10.1177/10105395251318112

Nar Bahadur Rai, Kinley Penjor, Amber Bahadur Gurung, Tshewang Samdrup, Yonten Dargay, Samzang Samzang, Kinley Wangdi

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Abstract

Tuberculosis (TB) is one of the major public health issues in Bhutan. This study aimed to evaluate epidemiology of TB and predictors of poor treatment outcomes in Sarpang District, Bhutan. A retrospective cohort study was conducted using TB case-based surveillance data of Sarpang District from 2005 to 2021. The outcome of interest was poor treatment outcome. The potential predictors were analyzed using logistic regression. A total of 1704 TB cases were analyzed in this study. The poor outcome in this study was 6.6% with 2.6% deaths due to TB. The patients older than 65 years (adjusted odds ratio [AOR] = 3.58) and sputum non-conversion in the second month with acid-fast bacilli results of scanty (AOR = 3.08), 1+ (AOR = 7.12), and 2+ (AOR = 21.05) were the significant predictors of poor treatment outcome. Therefore, older age and sputum non-conversion in the second month should be given priority.

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不丹 Sarpang 地区结核病患者的流行病学概况及治疗效果不佳的风险因素：17年回顾性研究。

结核病是不丹的主要公共卫生问题之一。这项研究旨在评估不丹Sarpang地区结核病的流行病学和不良治疗结果的预测因素。利用2005年至2021年沙邦地区基于结核病病例的监测数据进行了一项回顾性队列研究。结果感兴趣的是不良的治疗结果。使用逻辑回归分析潜在的预测因素。本研究共分析了1704例结核病例。本研究的不良预后为6.6%，其中2.6%因结核病死亡。年龄大于65岁的患者（校正优势比[AOR] = 3.58, 95%可信区间[CI] =[1.45, 7.90]）和第2个月痰液未转化且抗酸杆菌结果少（AOR = 3.08, 95% CI =[1.29, 7.34]）、1+ (AOR = 7.12, 95% CI =[3.06, 16.53])和2+ (AOR = 21.05, 95% CI =[5.56, 79.63])是治疗效果不良的显著预测因素。因此，年龄较大且痰液未转诊于第二个月者应优先考虑。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Asia-Pacific Journal of Public Health 医学-公共卫生、环境卫生与职业卫生

CiteScore

3.30

自引率

4.00%

发文量

147

审稿时长

6 months

期刊介绍： Asia-Pacific Journal of Public Health (APJPH) is a peer-reviewed, bimonthly journal that focuses on health issues in the Asia-Pacific Region. APJPH publishes original articles on public health related issues, including implications for practical applications to professional education and services for public health and primary health care that are of concern and relevance to the Asia-Pacific region.