Assessment of auditory and cochlear function in non segmental vitiligo patients: a case controlled study

IF 2.1 4区 医学 Q3 DERMATOLOGY Archives of Dermatological Research Pub Date : 2025-02-14 DOI:10.1007/s00403-025-03912-w
Kholoud Fayrouz A. El Gaml, Hassan Abou Khodair Mohamed, Ramadan M. Eldahshan, Takwa A. Gabr, Mohamed L. Elsaie
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Abstract

Vitiligo associated auditory problems have been reported in some patients. Few studies had reported the audiological manifestations. This studyaimed to assess the auditory and cochlear function in non-segmental vitiligo patients. This case control study was carried out on 120 subjects. Participants were divided into; Group 1, which consisted of 60 adults suffering from non-segmental vitiligo, and Group 2, consisting of 60 healthy adults as a control group. Dermatological evaluation was by VIDA (Vitiligo Index of Disease Activity) and VASI (Vitiligo Area Scoring Index) scores. Otoscopic examination, Basic Audiological Evaluation, and Distortion Product Otoacoustic Emissions (DPOAEs) were assessed in all participants. Pure tone audiometry (PTA) was calculated in both ears at different frequencies (250–8000 Hz) and results showed significantly lower thresholds at all tested frequencies in the control group when compared with the study group. DPOAEs, result showed significant lower DPOAE in both right and left ears of the patients with non-segmental vitiligo when compared with normal hearing control group. Hearing evaluation procedures revealed lower hearing threshold of the inner ears in patients with non-segmental vitiligo when compared with control groups.

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评估非节段性白癜风患者的听觉和耳蜗功能:一项病例对照研究。
白癜风相关的听力问题已报道在一些患者。很少有研究报道其听力学表现。本研究旨在评估非节段性白癜风患者的听觉和耳蜗功能。本病例对照研究对120名受试者进行。参与者被分为;第一组由60名患有非节段性白癜风的成年人组成,第二组由60名健康成年人组成作为对照组。皮肤病学评价采用白癜风疾病活动指数(VIDA)和白癜风区域评分指数(VASI)评分。对所有参与者进行耳镜检查、基本听力学评估和畸变产物耳声发射(dpoae)评估。在不同频率(250- 8000hz)下计算双耳纯音测听(PTA),结果显示,与研究组相比,对照组在所有测试频率下的阈值均显着降低。结果显示,与听力正常对照组相比,非节段性白癜风患者左右耳DPOAE均明显降低。听力评估程序显示,与对照组相比,非节段性白癜风患者的内耳听力阈值较低。
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来源期刊
CiteScore
4.10
自引率
3.30%
发文量
30
审稿时长
4-8 weeks
期刊介绍: Archives of Dermatological Research is a highly rated international journal that publishes original contributions in the field of experimental dermatology, including papers on biochemistry, morphology and immunology of the skin. The journal is among the few not related to dermatological associations or belonging to respective societies which guarantees complete independence. This English-language journal also offers a platform for review articles in areas of interest for dermatologists and for publication of innovative clinical trials.
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