Cheng Feng, Shouzhe Zhu, Shuang Yang, Feifei Xing, Xiang Wang
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引用次数: 0
Abstract
Transient assemblies generated by fuel consumption biomacromolecules are essential for biological processes. Although artificial transient assemblies have been investitigated extensively in recent years, molecules mimicking secondary structures of biomacromolecules have been rarely exploited to construct fuel driving transient systems. Herein, we reported a transient foldaxane system using a double helical aromatic oligoamide. The aromatic oligoamide adopts a mixture of parallel and antiparallel conformation in solution, whilst the presence of a molecular thread drives the conversion of parallel double helix to antiparallel double helix and the formation of foldaxane between antiparallel double helix and the thread. 4-Methylpiperidine can cleave the thread to regenerate free parallel and antiparallel double helix. The formation of foldaxane can be fueled with this thread for upto three cycles. These results open up a possibility to introduce dissipative behavior into abiotic quaternary structures to generate life-like dynamic systems.
期刊介绍：
Organic Chemistry Frontiers is an esteemed journal that publishes high-quality research across the field of organic chemistry. It places a significant emphasis on studies that contribute substantially to the field by introducing new or significantly improved protocols and methodologies. The journal covers a wide array of topics which include, but are not limited to, organic synthesis, the development of synthetic methodologies, catalysis, natural products, functional organic materials, supramolecular and macromolecular chemistry, as well as physical and computational organic chemistry.
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