Integrative Omics Approaches in Cardiovascular Disease Research: Current Trends and Future Directions

IF 5.3 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Canadian Journal of Cardiology Pub Date : 2025-08-01 Epub Date: 2025-02-12 DOI:10.1016/j.cjca.2025.02.016
Shekoofeh Saboktakin Rizi MD , Aleksandra Stamenkovic PhD , Amir Ravandi MD, PhD
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心血管疾病研究中的综合组学方法:当前趋势和未来方向。
心血管疾病(CVD)仍然是世界范围内死亡的主要原因,需要对其复杂的病理生理有更深入的了解。组学技术——基因组学、转录组学、蛋白质组学和代谢组学——已经彻底改变了心血管研究,使生物系统在多个分子水平上的高通量分析成为可能。这些工具通过揭示心血管疾病的分子机制,推动了精准医疗的发展。传统上,研究遵循自上而下的方法,分析广泛的心血管子系统。然而,现代高通量技术支持自下而上的方法,首先检查分子成分,然后将发现整合到更大的系统中。这种由大数据驱动的范式转变正在改变心血管研究,并为更精确、个性化的治疗铺平道路。
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来源期刊
Canadian Journal of Cardiology
Canadian Journal of Cardiology 医学-心血管系统
CiteScore
9.20
自引率
8.10%
发文量
546
审稿时长
32 days
期刊介绍: The Canadian Journal of Cardiology (CJC) is the official journal of the Canadian Cardiovascular Society (CCS). The CJC is a vehicle for the international dissemination of new knowledge in cardiology and cardiovascular science, particularly serving as the major venue for Canadian cardiovascular medicine.
期刊最新文献
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