Correspondence to "The association between cigarette smoking and dementia with Lewy bodies".

Abstract

Our pathology-validated study on Parkinson's disease aligns with recently reported findings in dementia with Lewy bodies regarding an inverse association with smoking. Understanding this epidemiological relationship is crucial for uncovering potential pathogenic mechanisms in α-synucleinopathies, emphasizing the need for rigorous studies that integrate neuropathological validation and address diagnostic uncertainty.