[Age-related peculiarities of adrenergic regulation of the contractility and pump function of the heart].

Zeitschrift fur Alternsforschung Pub Date : 1988-11-01
O V Korkusko, G Z Moroz
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Abstract

The pharmacodynamics of adrenaline were investigated with respect to the adrenergic regulation of the contractility, of the pumping function and of the systolic function of the heart, aiming at the examination of age particularities. The results show that the positively effect of adrenaline becomes less with increasing age. The arrhythmogenic effect of the preparation is described, just as its effect on blood pressure regulation. The results are discussed in detail.

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[心脏收缩力和泵功能肾上腺素能调节的年龄相关特性]。
从肾上腺素对心脏收缩力、泵血功能和收缩功能的调节作用出发,探讨了肾上腺素的药效学。结果表明,随着年龄的增长,肾上腺素的积极作用逐渐减弱。本文描述了该制剂的致心律失常作用,正如其对血压调节的作用一样。对结果进行了详细的讨论。
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