H. S. Lalithamba, G. Nagendra, M. Ramya, G. K. Prashanth
{"title":"Tetrazoles: Versatile Biomimetics of Peptides","authors":"H. S. Lalithamba, G. Nagendra, M. Ramya, G. K. Prashanth","doi":"10.1134/S1070427224080056","DOIUrl":null,"url":null,"abstract":"<p>The present communication reflects different approaches for the synthesis of tetrazole biomimetic replacement of carboxylic acid. Tetrazole is one among the many isosteres that represent the true replacement to carboxylic acid. Tetrazole tethered molecules exhibit many biological activities and catalytic activities in organic transformations. Synthetic methodologies for the construction of free tetrazole, substituted tetrazole, fused tetrazoles, etc., were substantiated that would offer a platform to encompass the researcher to avail complete information on the tetrazoles.</p>","PeriodicalId":757,"journal":{"name":"Russian Journal of Applied Chemistry","volume":"97 8","pages":"633 - 654"},"PeriodicalIF":0.6000,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Journal of Applied Chemistry","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1134/S1070427224080056","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
引用次数: 0
Abstract
The present communication reflects different approaches for the synthesis of tetrazole biomimetic replacement of carboxylic acid. Tetrazole is one among the many isosteres that represent the true replacement to carboxylic acid. Tetrazole tethered molecules exhibit many biological activities and catalytic activities in organic transformations. Synthetic methodologies for the construction of free tetrazole, substituted tetrazole, fused tetrazoles, etc., were substantiated that would offer a platform to encompass the researcher to avail complete information on the tetrazoles.
期刊介绍:
Russian Journal of Applied Chemistry (Zhurnal prikladnoi khimii) was founded in 1928. It covers all application problems of modern chemistry, including the structure of inorganic and organic compounds, kinetics and mechanisms of chemical reactions, problems of chemical processes and apparatus, borderline problems of chemistry, and applied research.