A. G. Kazakov, D. V. Pavlova, I. A. Ushakov, E. A. Nesterov, V. S. Skuridin, E. A. Odintsova, S. E. Vinokurov, B. F. Myasoedov
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引用次数: 0
Abstract
Conditions were determined for preparing a suspension of detonation synthesis nanodiamonds (NDs) with immobilized scandium in solutions, meeting the requirements to solutions for intravenous administration of radiopharmaceuticals based on the medicinal isotopes 44Sc and 47Sc. The possibility of the quantitative binding of scandium with ND samples in isotonic solutions having the required pH and containing the minimal ND amount was demonstrated. The Freundlich and Langmuir adsorption isotherm parameters and ΔG of adsorption were determined for the most promising ND sample under the optimum conditions. The conditions found for preparing NDs with immobilized scandium isotopes will allow in vivo studies in the future.
期刊介绍：
Radiochemistry is a journal that covers the theoretical and applied aspects of radiochemistry, including basic nuclear physical properties of radionuclides; chemistry of radioactive elements and their compounds; the occurrence and behavior of natural and artificial radionuclides in the environment; nuclear fuel cycle; radiochemical analysis methods and devices; production and isolation of radionuclides, synthesis of labeled compounds, new applications of radioactive tracers; radiochemical aspects of nuclear medicine; radiation chemistry and after-effects of nuclear transformations.
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