Development of Bioactive Patches From Aloe Vera and Nata De Coco for Wound Dressing Applications

Q3 Materials Science Macromolecular Symposia Pub Date : 2025-02-17 DOI:10.1002/masy.202300235

Siti Maznah binti Kabeb, Nurlin binti Abu Samah, Nurjannah binti Salim, Farah Hanani Zulkifli

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引用次数: 0

Abstract

This study focuses on the development and characterization of bioactive patches derived from Aloe Vera (AV) and Nata De Coco (NDC) for advanced wound dressing applications. Utilizing the solution casting method, biocomposite films are developed using polyvinyl alcohol (PVA) with varied bio-filler content (2%−10%) w/w. Fourier-transform infrared (FTIR) analysis confirms the miscibility and compatibility of PVA and bio-fillers via intermolecular hydrogen bonding. PVA/NDC10 demonstrates the highest water-holding capacity (WHC), exhibiting an increase from 157.17% (neat PVA) to 286.01%, resulting in an 82.0% enhancement. Conversely, increasing NDC content leads to a gradual decrease in tensile strength. Notably, the hybrid biocomposite film (PVA/AV/NDC) shows a significant 20.82% improvement in tensile strength, reaching 30.79 MPa. The study underscores the promise of AV and NDC bioactive patches for advanced wound dressing. Additionally, the hybrid approach shows synergistic improvements in water retention and mechanical strength, offering a comprehensive solution for effective wound management.

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芦荟和椰子树生物活性贴剂在伤口敷料中的应用

本研究的重点是开发和表征从芦荟（AV）和椰子树（NDC）中提取的生物活性贴片，用于高级伤口敷料应用。采用溶液浇铸法，采用不同生物填料含量（2% ~ 10%）w/w的聚乙烯醇（PVA）制备生物复合膜。傅里叶变换红外（FTIR）分析通过分子间氢键证实了PVA与生物填料的混溶性和相容性。PVA/NDC10的持水能力（WHC）最高，从157.17%（纯PVA）增加到286.01%，提高了82.0%。相反，NDC含量的增加导致拉伸强度逐渐降低。其中，杂化生物复合膜（PVA/AV/NDC）的拉伸强度提高了20.82%，达到30.79 MPa。该研究强调了AV和NDC生物活性贴片用于晚期伤口敷料的前景。此外，混合方法在保水性和机械强度方面表现出协同改善，为有效的伤口管理提供了全面的解决方案。

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来源期刊

Macromolecular Symposia Materials Science-Polymers and Plastics

CiteScore

1.50

自引率

0.00%

发文量

226

期刊介绍： Macromolecular Symposia presents state-of-the-art research articles in the field of macromolecular chemistry and physics. All submitted contributions are peer-reviewed to ensure a high quality of published manuscripts. Accepted articles will be typeset and published as a hardcover edition together with online publication at Wiley InterScience, thereby guaranteeing an immediate international dissemination.