Jena Velji-Ibrahim, Piyush Nathani, Harsh K Patel, Prateek Sharma
{"title":"GLP-1 receptor agonist use does not increase risk of respiratory complications post-endoscopy.","authors":"Jena Velji-Ibrahim, Piyush Nathani, Harsh K Patel, Prateek Sharma","doi":"10.1055/a-2487-2937","DOIUrl":null,"url":null,"abstract":"<p><strong>Background and study aims: </strong>Data on respiratory complications associated with GLP-1 receptor agonist (GLP-1 RA) use before endoscopic procedures are limited.</p><p><strong>Patients and methods: </strong>We conducted a retrospective cohort study using TriNetX in adults with diabetes or obesity on GLP-1 RAs within 3 months of endoscopy, comparing them with non-GLP-1 RA users. Propensity score matching and Cox proportional hazards models were used to assess outcomes.</p><p><strong>Results: </strong>Among 46,948 patients, no significant differences in post-endoscopy aspiration pneumonitis (hazard ratio [HR] 0.92, 95% confidence interval [CI] 0.54-1.56) or pneumonia (HR 1.01, 95% CI 0.83-1.24) were found between groups.</p><p><strong>Conclusions: </strong>GLP-1 RA use before endoscopy does not increase respiratory complications, supporting continued preoperative medication use.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"13 ","pages":"a24872937"},"PeriodicalIF":2.3000,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11827728/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Endoscopy International Open","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1055/a-2487-2937","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Background and study aims: Data on respiratory complications associated with GLP-1 receptor agonist (GLP-1 RA) use before endoscopic procedures are limited.
Patients and methods: We conducted a retrospective cohort study using TriNetX in adults with diabetes or obesity on GLP-1 RAs within 3 months of endoscopy, comparing them with non-GLP-1 RA users. Propensity score matching and Cox proportional hazards models were used to assess outcomes.
Results: Among 46,948 patients, no significant differences in post-endoscopy aspiration pneumonitis (hazard ratio [HR] 0.92, 95% confidence interval [CI] 0.54-1.56) or pneumonia (HR 1.01, 95% CI 0.83-1.24) were found between groups.
Conclusions: GLP-1 RA use before endoscopy does not increase respiratory complications, supporting continued preoperative medication use.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
