Fetus in fetu: the importance of autopsy in uncovering hidden abnormalities.

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL BMJ Case Reports Pub Date : 2025-02-16 DOI:10.1136/bcr-2024-263111
Umamaheswari Gurusamy, Vartika Goel, Shyama Devadasan
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Abstract

Fetus in fetu (FIF) is a rare anomaly of embryogenesis in which a malformed parasitic twin is found within the body of the normally developed host twin. It has a reported incidence of 1 per 500 000 births with a 2:1 male predominance. The authors present a unique case of FIF, where autopsy investigation played a pivotal role in identifying this exceptionally rare anomaly, rarely documented in the literature. A primigravida woman in her early 20s was diagnosed with FIF at 13+3 weeks of gestation. She opted for medical termination of her pregnancy. The postmortem examination confirmed the diagnosis of FIF. Malformations in both fetuses, namely, partial urorectal septum malformation in the parasitic twin and heterotaxy syndrome in the host twin, were unmasked by fetal autopsy.The significance of autopsy examination in FIF cases is underscored by our case, as it facilitates the diagnosis of this rare entity and the reporting of congenital anomalies in the aforementioned.

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胎中胎:尸检在发现隐藏异常中的重要性。
胎中胎(FIF)是一种罕见的胚胎发生异常,在正常发育的宿主双胞胎体内发现畸形寄生双胞胎。据报道,发病率为每50万例新生儿中有1例,男性占2:1的优势。作者提出了一个独特的FIF病例,其中尸检调查在确定这种异常罕见的异常中发挥了关键作用,很少在文献中记录。一名20岁出头的初产妇在妊娠13+3周时被诊断为FIF。她选择用药物终止妊娠。尸检确诊为FIF。两个胎儿的畸形,即寄生双胞胎的部分尿直肠隔畸形和宿主双胞胎的异位综合征,都是通过胎儿尸检发现的。我们的病例强调了尸检在FIF病例中的重要性,因为它有助于诊断这种罕见的实体并报告上述先天性异常。
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来源期刊
BMJ Case Reports
BMJ Case Reports Medicine-Medicine (all)
CiteScore
1.40
自引率
0.00%
发文量
1588
期刊介绍: BMJ Case Reports is an important educational resource offering a high volume of cases in all disciplines so that healthcare professionals, researchers and others can easily find clinically important information on common and rare conditions. All articles are peer reviewed and copy edited before publication. BMJ Case Reports is not an edition or supplement of the BMJ.
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