Kaitlin Benedict, Dallas J Smith, Angela Haczku, Amir A Zeki, Joy Hsu, Mitsuru Toda, Nicholas J Kenyon, George R Thompson
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引用次数: 0
Abstract
Background: The relationship between asthma and coccidioidomycosis has not been fully described. We have hypothesised that Coccidioides could trigger inflammatory airway responses, similar to other fungi.
Objectives: To estimate the frequency of new-onset asthma-related symptoms after coccidioidomycosis and identify potentially associated factors.
Patients/methods: We used a large health insurance claims database to identify patients with coccidiomycosis with and without an asthma diagnosis code or a short-acting β2 agonist prescription in the year after diagnosis.
Results: Thirteen per cent of 1657 patients with an asthma diagnosis code or a short-acting β2 agonist prescription (median 2.5 months later).
Conclusions: Increased healthcare provider awareness of asthma as a potential coccidioidomycosis complication could benefit patients, especially female patients and patients with severe pulmonary infection.
期刊介绍:
The journal Mycoses provides an international forum for original papers in English on the pathogenesis, diagnosis, therapy, prophylaxis, and epidemiology of fungal infectious diseases in humans as well as on the biology of pathogenic fungi.
Medical mycology as part of medical microbiology is advancing rapidly. Effective therapeutic strategies are already available in chemotherapy and are being further developed. Their application requires reliable laboratory diagnostic techniques, which, in turn, result from mycological basic research. Opportunistic mycoses vary greatly in their clinical and pathological symptoms, because the underlying disease of a patient at risk decisively determines their symptomatology and progress. The journal Mycoses is therefore of interest to scientists in fundamental mycological research, mycological laboratory diagnosticians and clinicians interested in fungal infections.