Analysis of continuous monitoring device data.

IF 1.2 4区 医学 Q4 PHARMACOLOGY & PHARMACY Journal of Biopharmaceutical Statistics Pub Date : 2025-02-16 DOI:10.1080/10543406.2025.2460455
Jin Wang, Javier Cabrera, Davit Sargsyan, Kanaka Tatikola, Kwok-Leung Tsui
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Abstract

This paper introduces a methodology for processing continuous monitoring device data, such as data from a wearable digital device or continuous telemetered data, to estimate outcomes like systolic blood pressure or treatment effects. One of the challenges of analyzing this type of data is to find a suitable binning or scaling to compress the information for improving outcome predictions. Another challenge is to select and weight the features to be included in the computational model. The new methodology consists of a combination of feature selection and feature weighting incorporated into the LASSO and the elastic net methods, which addresses both issues simultaneously. The compression of continuous data into weighted discretized data is a prominent issue in the development of AI methodology that is applied to wearable DHT devices. The new methodology was applied to a Fitbit data set from a Hong Kong elderly center study.

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连续监测装置数据分析。
本文介绍了一种处理连续监测设备数据的方法,例如来自可穿戴数字设备或连续遥测数据的数据,以估计收缩压或治疗效果等结果。分析这类数据的挑战之一是找到合适的分组或缩放来压缩信息,以改进结果预测。另一个挑战是选择和加权要包含在计算模型中的特征。新方法将特征选择和特征加权结合到LASSO方法和弹性网方法中,同时解决了这两个问题。将连续数据压缩为加权离散数据是应用于可穿戴DHT设备的人工智能方法开发中的一个突出问题。新方法应用于来自香港老年中心研究的Fitbit数据集。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Biopharmaceutical Statistics
Journal of Biopharmaceutical Statistics 医学-统计学与概率论
CiteScore
2.50
自引率
18.20%
发文量
71
审稿时长
6-12 weeks
期刊介绍: The Journal of Biopharmaceutical Statistics, a rapid publication journal, discusses quality applications of statistics in biopharmaceutical research and development. Now publishing six times per year, it includes expositions of statistical methodology with immediate applicability to biopharmaceutical research in the form of full-length and short manuscripts, review articles, selected/invited conference papers, short articles, and letters to the editor. Addressing timely and provocative topics important to the biostatistical profession, the journal covers: Drug, device, and biological research and development; Drug screening and drug design; Assessment of pharmacological activity; Pharmaceutical formulation and scale-up; Preclinical safety assessment; Bioavailability, bioequivalence, and pharmacokinetics; Phase, I, II, and III clinical development including complex innovative designs; Premarket approval assessment of clinical safety; Postmarketing surveillance; Big data and artificial intelligence and applications.
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