{"title":"Gram-Scalable Solvent-Free One-Pot Three-Component Synthesis of 2-Arylamino-3-Cyanopyridines","authors":"Afsaneh Zonouzi , Fatemeh Hosseinzadeh","doi":"10.1080/10406638.2024.2401029","DOIUrl":null,"url":null,"abstract":"<div><div>Organic compounds that can show fluorescence are utilized for numerous applications. Scalable synthetic routes for such compounds are a great part of academic as well as technological investigations in this area. In addition to fluorescent properties, pyridine compounds have been proven for other applications, especially in biological studies. A one-pot synthetic procedure is presented and 16 (14 new) compounds of the 2-arylamino-3-cyanopiridine family are being reported for the first time. Analytical methods including CHN, NMR (<sup>1</sup>H and <sup>13</sup>C), IR, and MS were used to characterize the newly reported compounds. They all show blue to green fluorescence when irradiated with UV light. A scalable approach is also presented with more than 95% yield for obtaining these compounds with a fairly facile workup.</div></div>","PeriodicalId":20303,"journal":{"name":"Polycyclic Aromatic Compounds","volume":"45 2","pages":"Pages 205-217"},"PeriodicalIF":2.4000,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polycyclic Aromatic Compounds","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S1040663824000496","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
Organic compounds that can show fluorescence are utilized for numerous applications. Scalable synthetic routes for such compounds are a great part of academic as well as technological investigations in this area. In addition to fluorescent properties, pyridine compounds have been proven for other applications, especially in biological studies. A one-pot synthetic procedure is presented and 16 (14 new) compounds of the 2-arylamino-3-cyanopiridine family are being reported for the first time. Analytical methods including CHN, NMR (1H and 13C), IR, and MS were used to characterize the newly reported compounds. They all show blue to green fluorescence when irradiated with UV light. A scalable approach is also presented with more than 95% yield for obtaining these compounds with a fairly facile workup.
期刊介绍：
The purpose of Polycyclic Aromatic Compounds is to provide an international and interdisciplinary forum for all aspects of research related to polycyclic aromatic compounds (PAC). Topics range from fundamental research in chemistry (including synthetic and theoretical chemistry) and physics (including astrophysics), as well as thermodynamics, spectroscopy, analytical methods, and biology to applied studies in environmental science, biochemistry, toxicology, and industry. Polycyclic Aromatic Compounds has an outstanding Editorial Board and offers a rapid and efficient peer review process, as well as a flexible open access policy.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
