Dorota Dziewulska, Anna Potulska-Chromik, Piotr Szczudlik
{"title":"Enteric neuropathy - when a surgeon is not immediately needed.","authors":"Dorota Dziewulska, Anna Potulska-Chromik, Piotr Szczudlik","doi":"10.5114/fn.2024.134027","DOIUrl":null,"url":null,"abstract":"<p><p>Peripheral neuropathies with involvement of the autonomic nervous system are a recognized cause of gastrointestinal dysmotility. We describe a patient with chronic intestinal pseudo-obstruction (CIPO) in the course of chronic inflammatory demyelinating neuropathy and a complicated diagnostic procedure. Diagnostics and therapy of CIPO continue to pose a significant challenge for clinicians. The disease should be considered in patients presenting with clinical features of intestinal obstruction without radiological evidence of a mechanical obstacle. In these patients, the diagnosis is usually confirmed by histological examination of a full-thickness intestinal biopsy. However, the high rate of misdiagnosis means that CIPO patients may not be treated properly and may undergo unnecessary abdominal surgery.</p>","PeriodicalId":12370,"journal":{"name":"Folia neuropathologica","volume":"62 4","pages":"451-455"},"PeriodicalIF":1.5000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Folia neuropathologica","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.5114/fn.2024.134027","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Peripheral neuropathies with involvement of the autonomic nervous system are a recognized cause of gastrointestinal dysmotility. We describe a patient with chronic intestinal pseudo-obstruction (CIPO) in the course of chronic inflammatory demyelinating neuropathy and a complicated diagnostic procedure. Diagnostics and therapy of CIPO continue to pose a significant challenge for clinicians. The disease should be considered in patients presenting with clinical features of intestinal obstruction without radiological evidence of a mechanical obstacle. In these patients, the diagnosis is usually confirmed by histological examination of a full-thickness intestinal biopsy. However, the high rate of misdiagnosis means that CIPO patients may not be treated properly and may undergo unnecessary abdominal surgery.
期刊介绍:
Folia Neuropathologica is an official journal of the Mossakowski Medical Research Centre Polish Academy of Sciences and the Polish Association of Neuropathologists. The journal publishes original articles and reviews that deal with all aspects of clinical and experimental neuropathology and related fields of neuroscience research. The scope of journal includes surgical and experimental pathomorphology, ultrastructure, immunohistochemistry, biochemistry and molecular biology of the nervous tissue. Papers on surgical neuropathology and neuroimaging are also welcome. The reports in other fields relevant to the understanding of human neuropathology might be considered.