[Peripheral artery disease II: femoropopliteal lesions].

IF 0.6 Innere Medizin (Heidelberg, Germany) Pub Date : 2025-03-01 Epub Date: 2025-02-17 DOI:10.1007/s00108-025-01858-9
Christos Rammos, Tienush Rassaf, Grigorios Korosoglou
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Abstract

The endovascular treatment of the femoropopliteal segment is the most frequent revascularization option in patients with peripheral arterial occlusive disease (PAOD); however, the plain old balloon angioplasty has limitations, especially in complex and calcified lesions, and can lead to dissections and recoil. In order to improve the technical success and the efficacy of the endovascular treatment in complex, sometimes severely calcified or thrombotic lesions or also in lesions in mobile segments, a lesion preparation strategy before the actual lesion treatment is frequently applied. Lesion preparation methods include atherectomy, thrombectomy or intravascular lithotripsy. Through lesion preparation plaques and/or organized thrombi can be minimally invasively removed or calcium deposits can be even fragmented with low threshold barotrauma, without damaging the vessel wall. Subsequently, the definitive treatment of the lesion can be carried out using drug-coated balloons (DCB), bare metal stents (BMS), drug-eluting stents (DES) or a combination of these. Due to the heterogeneity of patient and lesion characteristics, no 'one fits all' strategy is so far available; however, the choice of the appropriate instruments should be carried out based on the patient and lesion characteristics present, whereby for the lesion-specific parameters the extent of the morphology and underlying pathology plays an important role.

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外周动脉疾病II:股腘动脉病变。
股腘段血管内治疗是外周动脉闭塞性疾病(PAOD)患者最常见的血运重建术;然而,普通的球囊血管成形术有局限性,特别是在复杂和钙化的病变中,可能导致剥离和后坐。为了提高复杂的、有时严重钙化或血栓性病变或活动节段病变的血管内治疗的技术成功率和疗效,在实际病变治疗之前经常采用病变准备策略。病变准备方法包括动脉粥样硬化切除术、血栓切除术或血管内碎石术。通过病变准备,可以微创去除斑块和/或有组织的血栓,低阈值气压创伤甚至可以粉碎钙沉积,而不会损伤血管壁。随后,病变的最终治疗可以使用药物包被球囊(DCB)、裸金属支架(BMS)、药物洗脱支架(DES)或这些的组合进行。由于患者和病变特征的异质性,目前还没有“放之四海而皆准”的策略;然而,适当的器械的选择应根据患者和病变的特征进行,因此对于病变特异性参数,形态学和基础病理学的程度起着重要作用。
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