The epidemiological, etiological, and clinical comparisons of primary and recurrent Dupuytren's contractures.

Erol Kozanoğlu, Fethi Sarper Mete, Bora Edim Akalın, Dicle Aksoyler, Ömer Berköz, Ufuk Emekli, Rıfat Atilla Arıncı
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Abstract

Background: Dupuytren's contracture is characterized by the thickening of the palmar fascia. Although extensive literature exists on this disease, changes in lifestyle necessitate the re-evaluation of its epidemiology, etiology, and clinical features. This study aims to revise the current characteristics of Dupuytren's contracture and to explore potential relationships between these characteristics and recurrence.

Methods: Patients who underwent surgery for Dupuytren's contracture between January 2014 and December 2016 were included in this study. Electronic health records were reviewed to collect data on gender, age at surgery, age at the first signs of the disease, dominant hand, profession, cigarette and alcohol consumption, comorbidities and their treatments, the affected hand and digit, operative technique, type of anesthesia, degree of joint contracture severity, and presence of recurrence. Patients with and without recurrence were compared.

Results: A total of 69 patients were included (60 males, nine females) with a mean age of 68.4 years (range: 51-90 years). Unilateral hand involvement was significantly more common. Recurrence occurred in seven patients (six males, one female). Comparison between patients with and without recurrence revealed that involvement of the first ray was significantly associated with recurrence. Partial palmar fasciectomy was the most commonly performed surgical procedure for recurrence treatment. No other significant differences were observed between the groups. The initial contracture angles of the metacarpophalangeal joints were higher compared to those observed in recurrence, whereas the proximal and distal interphalangeal joints were similar.

Conclusion: No new recurrence-independent epidemiological, etiological, or clinical factors were identified for Dupuytren's contracture. However, first ray involvement was significantly associated with recurrence. Partial palmar fasciectomy was the primary surgical approach for treating recurrence. Metacarpophalangeal recurrence was less severe than the initial disease, while proximal and distal interphalangeal recurrences were similar in severity.

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原发性和复发性杜普伊特伦挛缩症的流行病学、病因学和临床比较。
背景:Dupuytren挛缩以掌筋膜增厚为特征。虽然有大量关于该病的文献,但生活方式的改变需要对其流行病学、病因学和临床特征进行重新评估。本研究旨在修订Dupuytren挛缩的现有特征,并探讨这些特征与复发之间的潜在关系。方法:选取2014年1月至2016年12月期间因Dupuytren挛缩手术的患者为研究对象。对电子健康记录进行审查,以收集性别、手术年龄、首次出现疾病迹象的年龄、惯用手、职业、吸烟和饮酒、合并症及其治疗、受影响的手和手指、手术技术、麻醉类型、关节挛缩严重程度和复发的数据。比较有无复发的患者。结果:共纳入69例患者(男60例,女9例),平均年龄68.4岁(范围:51 ~ 90岁)。单侧手受累明显更常见。复发7例(6男1女)。有复发和无复发患者的比较显示,第一道射线受累与复发有显著相关性。部分掌筋膜切除术是复发治疗中最常用的手术方法。两组之间没有观察到其他显著差异。掌指关节的初始挛缩角度比复发时高,而近端和远端指间关节相似。结论:未发现与复发无关的Dupuytren挛缩的流行病学、病因学或临床因素。然而,一线受累与复发显著相关。部分掌筋膜切除术是治疗复发的主要手术方法。掌指关节复发的严重程度低于初始疾病,而近端和远端指间复发的严重程度相似。
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