{"title":"Fusarium Fungemia of T-lymphoblastic Lymphoma after HSCT: a Case Report and Review of the Literature.","authors":"Tianqi Qi, Qian Liu, Xinyue Liu, Qi Hao, Fuwei Wu, Chang Liu","doi":"10.7754/Clin.Lab.2024.240836","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Fusarium species is a facultative pathogen capable of causing invasive infections in patients with hematological malignancies after allogeneic hematopoietic stem cell transplantation (HSCT).</p><p><strong>Methods: </strong>We retrospectively analyzed a case of T-lymphoblastic lymphoma combined with disseminated fusariosis after HSCT in our hospital. Case reports of Fusarium fungemia in patients with hematological disorders over the past 20 years in Asia were reviewed.</p><p><strong>Results: </strong>Despite undergoing treatment with a combination of amphotericin B and voriconazole, the patient ultimately succumbed to multiple organ failure.</p><p><strong>Conclusions: </strong>Fusarium fungemia poses a fatal outcome. The adequate courses of antifungal medications are crucial.</p>","PeriodicalId":10384,"journal":{"name":"Clinical laboratory","volume":"71 2","pages":""},"PeriodicalIF":0.7000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical laboratory","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.7754/Clin.Lab.2024.240836","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICAL LABORATORY TECHNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Fusarium species is a facultative pathogen capable of causing invasive infections in patients with hematological malignancies after allogeneic hematopoietic stem cell transplantation (HSCT).
Methods: We retrospectively analyzed a case of T-lymphoblastic lymphoma combined with disseminated fusariosis after HSCT in our hospital. Case reports of Fusarium fungemia in patients with hematological disorders over the past 20 years in Asia were reviewed.
Results: Despite undergoing treatment with a combination of amphotericin B and voriconazole, the patient ultimately succumbed to multiple organ failure.
Conclusions: Fusarium fungemia poses a fatal outcome. The adequate courses of antifungal medications are crucial.
期刊介绍：
Clinical Laboratory is an international fully peer-reviewed journal covering all aspects of laboratory medicine and transfusion medicine. In addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies. The journal publishes original articles, review articles, posters, short reports, case studies and letters to the editor dealing with 1) the scientific background, implementation and diagnostic significance of laboratory methods employed in hospitals, blood banks and physicians'' offices and with 2) scientific, administrative and clinical aspects of transfusion medicine and 3) in addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies.
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