Unilateral Leg Swelling and Liver Enzyme Elevation in an Adolescent.

IF 6.4 2区 医学 Q1 PEDIATRICS Pediatrics Pub Date : 2025-02-19 DOI:10.1542/peds.2024-067246
Gabrielle Horner, Grace Luger, Mary McGrath, Anita Sharma, David A Bloom, Victoria Shakhin
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Abstract

A previously healthy 15-year-old female developed sudden onset right lower extremity swelling, pain, and erythematous linear streaking from the ankle to mid-thigh. Duplex venous ultrasound revealed multiple superficial and deep venous thrombi in the right lower extremity. Incidentally, the patient was also noted to have elevated transaminases and a microcytic anemia with significant iron deficiency. Additional evaluation ultimately led to the diagnosis of 2 distinct but interconnected chronic conditions, one of which progressed to requiring liver transplantation.

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一例青少年单侧腿部肿胀和肝酶升高。
先前健康的15岁女性突然出现右下肢肿胀、疼痛和从脚踝到大腿中部的红斑线状条纹。双腔静脉超声显示右下肢多发浅、深静脉血栓。顺便提一下,患者还注意到转氨酶升高和小细胞性贫血伴明显缺铁。额外的评估最终导致了两种不同但相互关联的慢性疾病的诊断,其中一种发展到需要肝移植。
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来源期刊
Pediatrics
Pediatrics 医学-小儿科
CiteScore
12.80
自引率
5.00%
发文量
791
审稿时长
2-3 weeks
期刊介绍: The Pediatrics® journal is the official flagship journal of the American Academy of Pediatrics (AAP). It is widely cited in the field of pediatric medicine and is recognized as the leading journal in the field. The journal publishes original research and evidence-based articles, which provide authoritative information to help readers stay up-to-date with the latest developments in pediatric medicine. The content is peer-reviewed and undergoes rigorous evaluation to ensure its quality and reliability. Pediatrics also serves as a valuable resource for conducting new research studies and supporting education and training activities in the field of pediatrics. It aims to enhance the quality of pediatric outpatient and inpatient care by disseminating valuable knowledge and insights. As of 2023, Pediatrics has an impressive Journal Impact Factor (IF) Score of 8.0. The IF is a measure of a journal's influence and importance in the scientific community, with higher scores indicating a greater impact. This score reflects the significance and reach of the research published in Pediatrics, further establishing its prominence in the field of pediatric medicine.
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