Pancreatic resection for metachronous colorectal cancer metastases: a case series multicenter study

IF 1.6 4区 医学 Q3 SURGERY ANZ Journal of Surgery Pub Date : 2025-02-20 DOI:10.1111/ans.70027
Francesco Palmieri MD, Francesco Lancellotti MD, Francesco Ferrara MD, Thomas Satyadas MD, Davide Gobatti MD, Luis Felipe Abreu de Carvalho MD, Filip Gryspeerdt MD, Grazia Conte MD, Federico Mocchegiani MD, Roberto Sampietro MD, Pierpaolo Sileri MD
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Abstract

Background

Pancreas resection for metachronous colorectal cancer metastasis is episodic and the role of surgery in the management of these patients is still debated.

Methods

We recruited seven patients from three different centres and analyzed 30-day morbidity and mortality, oncological outcomes at 6 and 12 months.

Results

There was no postoperative mortality. Complications occurred in two patients (28,6%). All patients completed at least a 12-months follow-up. At 6-month follow-up, only one patient had a recurrence. At 12-month follow-up, no patients died for disease recurrence and one more patient had a new recurrence.

Conclusion

Our series supports the feasibility and safety of pancreas resection in metastatic colorectal cancer suggesting that radical resection may improve the patient's prognosis.

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胰腺切除术治疗异时性结直肠癌转移:一项病例系列多中心研究。
背景:胰腺切除术治疗异时性结直肠癌转移是偶发性的,手术在治疗这些患者中的作用仍然存在争议。方法:我们从三个不同的中心招募了7名患者,分析了30天的发病率和死亡率,6个月和12个月的肿瘤预后。结果:无术后死亡。2例患者出现并发症(28.6%)。所有患者都完成了至少12个月的随访。在6个月的随访中,只有1例患者复发。在12个月的随访中,没有患者因疾病复发而死亡,另有1例患者复发。结论:本研究支持胰腺切除术治疗转移性结直肠癌的可行性和安全性,提示根治性切除可改善患者预后。
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来源期刊
ANZ Journal of Surgery
ANZ Journal of Surgery 医学-外科
CiteScore
2.50
自引率
11.80%
发文量
720
审稿时长
2 months
期刊介绍: ANZ Journal of Surgery is published by Wiley on behalf of the Royal Australasian College of Surgeons to provide a medium for the publication of peer-reviewed original contributions related to clinical practice and/or research in all fields of surgery and related disciplines. It also provides a programme of continuing education for surgeons. All articles are peer-reviewed by at least two researchers expert in the field of the submitted paper.
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