{"title":"Autopsy of a Patient with Hepatic Pleural Effusion Complicated by Pleurisy Associated with Sjögren's Syndrome: A Case Report.","authors":"Hikaru Mamizu, Ko Matsushima, Morihiro Kumagai, Chika Kuwana, Masanori Miyagatani, Yuusuke Tomita, Takuma Hatakeyama, Maiko Mamizu, Daisuke Ishikawa, Hidenori Kawakami, Toshiki Furukawa, Takashi Ishida, Chizuru Kaneko, Takeshi Sakai","doi":"10.2169/internalmedicine.4891-24","DOIUrl":null,"url":null,"abstract":"<p><p>We report the case of a 68-year-old man who presented with pleural effusion and dyspnea during treatment for alcoholic liver cirrhosis. The pleural effusion was transudative and it was diagnosed to be hepatic pleural effusion. Thoracic drainage was continued, but the amount of pleural fluid drainage did not decrease. The patient was strongly positive for antinuclear antibodies and anti-SS-A and anti-SS-B antibodies, thus leading us to suspect pleurisy caused by Sjögren's syndrome. Steroid administration decreased pleural drainage; however, cirrhosis progressed and the patient eventually died. An autopsy revealed pleurisy. Other causes may also be involved in treatment-resistant hepatic effusion.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":""},"PeriodicalIF":1.0000,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Internal Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2169/internalmedicine.4891-24","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
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Abstract
We report the case of a 68-year-old man who presented with pleural effusion and dyspnea during treatment for alcoholic liver cirrhosis. The pleural effusion was transudative and it was diagnosed to be hepatic pleural effusion. Thoracic drainage was continued, but the amount of pleural fluid drainage did not decrease. The patient was strongly positive for antinuclear antibodies and anti-SS-A and anti-SS-B antibodies, thus leading us to suspect pleurisy caused by Sjögren's syndrome. Steroid administration decreased pleural drainage; however, cirrhosis progressed and the patient eventually died. An autopsy revealed pleurisy. Other causes may also be involved in treatment-resistant hepatic effusion.
期刊介绍：
Internal Medicine is an open-access online only journal published monthly by the Japanese Society of Internal Medicine.
Articles must be prepared in accordance with "The Uniform Requirements for Manuscripts Submitted to Biomedical Journals (see Annals of Internal Medicine 108: 258-265, 1988), must be contributed solely to the Internal Medicine, and become the property of the Japanese Society of Internal Medicine. Statements contained therein are the responsibility of the author(s). The Society reserves copyright and renewal on all published material and such material may not be reproduced in any form without the written permission of the Society.
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