Functional Capacity Incorporating Dynamic Ventilation in Systemic Sclerosis: Agreement Analysis Between Performance on the 6-Minute Walk Test and Glittre-ADL Test.
Filipe da Silva Reis, Luis Felipe da Fonseca Reis, Isabelle da Nobrega Ferreira, Iasmim de Oliveira Farias, Laura Franco Pessoa, Lohana Resende da Costa, Hebert Olímpio Júnior, Arthur de Sá Ferreira, Agnaldo José Lopes
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引用次数: 0
Abstract
BackgroundFunctional capacity at submaximal exercise levels has become more popular as an outcome measure in systemic sclerosis (SSc). However, it is necessary to know the ventilatory requirements of the different field tests.ObjectivesTo verify the agreement of the ventilatory dynamics measured at submaximal exercise between the the Glittre-ADL test (TGlittre) and the 6-min walk test (6MWT) and, secondarily, to evaluate the correlations of these measurements with clinical and functional variables in women with SSc (wwSSc).MethodsThis was a cross-sectional study in which 30 wwSSc underwent the 6MWT and TGlittre while hooked to a device reading their ventilatory demand. Physical function was assessed on the Health Assessment Questionnaire Disability Index (HAQ-DI), and lung function was assessed by spirometry.ResultsThe median 6-min walking distance (6MWD) was 344 (282-410) metres, and 25 (83.3%) participants did not reach 80% of the predicted distance. The median TGlittre time was 147 (107-188) seconds, and 18 (60%) participants exceeded 120% of the predicted time. There was agreement between the two tests on the following variables: heart rate (ICC = 0.883, P < 0.0001), breathing reserve (ICC = 0.816, P < 0.0001), peripheral oxygen saturation (ICC = 0.752, P = 0.0009), inspiratory capacity (ICC = 0.690, P < 0.0001), and peak minute ventilation (ICC = 0.433, P = 0.007). There was a weak correlation between 6MWD and TGlittre time (rs=-0.353, P = 0.05). 6MWD correlated significantly with the HAQ-DI score (rs=-0.606, P = 0.0004) and forced vital capacity (FVC, rs = 0.427, P = 0.018). TGlittre time correlated significantly with HAQ-DI (rs = 0.440, P = 0.015) and FVC (rs=-0.404, P = 0.026).ConclusionIn wwSSc, the 6MWT and TGlittre have almost the same ventilatory requirements, although these patients perform worse in the 6MWT. 6MWD and TGlittre time are weakly correlated. Both 6MWD and TGlittre time are associated with physical function and lung function. Therefore, both tests should be used in clinical practice for the monitoring of these patients as they are complementary.
背景：亚极限运动水平下的功能能力作为系统性硬化症（SSc）的预后指标越来越受欢迎。然而，了解不同现场试验的通风要求是必要的。目的：验证格里特- adl试验（TGlittre）和6分钟步行试验（6MWT）在亚极限运动时测量的通气动力学的一致性，其次，评估这些测量与SSc女性（wwSSc）的临床和功能变量的相关性。方法：这是一项横断面研究，其中30名wwSSc接受了6MWT和TGlittre，同时连接到读取其通气需求的设备。采用健康评估问卷残疾指数（HAQ-DI）评估身体功能，肺活量测定法评估肺功能。结果：6分钟步行距离（6MWD）中位数为344（282-410）米，25名（83.3%）参与者未达到预测距离的80%。平均TGlittre时间为147（107-188）秒，18（60%）参与者超过了预测时间的120%。两项试验在以下变量上一致：心率（ICC = 0.883, P P = 0.0009），吸气量（ICC = 0.690, P P = 0.007）。6MWD与TGlittre时间呈弱相关（rs=-0.353, P = 0.05）。6MWD与HAQ-DI评分（rs=-0.606, P = 0.0004）、强迫肺活量（FVC, rs= 0.427, P = 0.018）显著相关。tglitt时间与HAQ-DI （rs= 0.440, P = 0.015）和FVC （rs=-0.404, P = 0.026）显著相关。结论：在wwSSc中，6MWT组和TGlittre组的通气需求几乎相同，尽管这些患者在6MWT组的表现更差。mwd与TGlittre时间呈弱相关。6MWD和TGlittre时间均与身体功能和肺功能相关。因此，在临床实践中，这两种检测都应用于监测这些患者，因为它们是互补的。
期刊介绍：
The Journal of Back and Musculoskeletal Rehabilitation is a journal whose main focus is to present relevant information about the interdisciplinary approach to musculoskeletal rehabilitation for clinicians who treat patients with back and musculoskeletal pain complaints. It will provide readers with both 1) a general fund of knowledge on the assessment and management of specific problems and 2) new information considered to be state-of-the-art in the field. The intended audience is multidisciplinary as well as multi-specialty.
In each issue clinicians can find information which they can use in their patient setting the very next day.
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