GLP-1 receptor agonists for weight loss for perimenopausal and postmenopausal women: current evidence.

IF 2.2 4区 医学 Q2 OBSTETRICS & GYNECOLOGY Current Opinion in Obstetrics & Gynecology Pub Date : 2025-04-01 Epub Date: 2025-02-25 DOI:10.1097/GCO.0000000000001015
Hana Mikdachi, Rebecca Dunsmoor-Su
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Abstract

Purpose of review: Glucagon-like peptide-1 receptor agonists (GLP-1 RA) have emerged as a leading pharmacologic for managing weight gain across most populations, including peri and postmenopausal women who frequently suffer from weight gain. There is a paucity of data about this specific population and how they respond to these medications. This review aims to discuss the data available about the use and effects of GLP-1 RAs in the peri and postmenopausal populations.

Recent findings: GLP-1 RAs are consistently the most effective pharmacologic for weight loss and can be a valuable tool for use in peri and postmenopausal women.

Summary: Additional research is needed to determine the risks and benefits and ideal use of GLP-1 RAs in peri and postmenopausal women.

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GLP-1受体激动剂对围绝经期和绝经后妇女的减肥作用:目前的证据
综述目的:胰高血糖素样肽-1受体激动剂(GLP-1 RA)已成为控制大多数人群体重增加的主要药物,包括经常遭受体重增加的围绝经期和绝经后妇女。关于这一特定人群以及他们对这些药物的反应的数据缺乏。本综述旨在讨论关于GLP-1 RAs在围绝经期和绝经后人群中的使用和作用的现有数据。最近的研究发现:GLP-1 RAs一直是最有效的减肥药理学,可以成为绝经期和绝经后妇女使用的有价值的工具。总结:需要进一步的研究来确定GLP-1 RAs在围绝经期和绝经后妇女中的风险和益处以及理想使用。
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来源期刊
CiteScore
4.10
自引率
0.00%
发文量
104
审稿时长
6-12 weeks
期刊介绍: ​​​​​​​Current Opinion in Obstetrics and Gynecology is a bimonthly publication offering a unique and wide ranging perspective on the key developments in the field. Each issue features hand-picked review articles from our team of expert editors. With eleven disciplines published across the year – including reproductive endocrinology, gynecologic cancer and fertility– every issue also contains annotated references detailing the merits of the most important papers.
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