Clinical efficacy of NIBS in enhancing neuroplasticity for stroke recovery

Abstract

Background

For stroke patients, a therapeutic approach named Non-invasive brain stimulation (NIBS) was applied and it has gained attention. This NIBS approach enhances the neuroplasticity and facilitates in functional Stroke Rehabilitation (SR) through regulating the brain activity. This NIBS has several advantages, but, the variability in patient responses, poor personalized treatment plans, and challenges in predicting rehabilitation stages may limit its clinical application. The generalized approaches are usually employed by the current SR methods. Here, the Patient-Centric (PC) factors that impacts neuroplasticity fails to be considered by the current SR methods. Thus, Real-Time mechanisms in monitoring and adapting to neural responses are lacking in the current SR methods.

Methods

A novel SR with Machine Learning (ML), (SR-ML) framework is suggested in this study. This suggested study integrates the patient-specific data, neuroimaging, and NIBS intervention models for the purpose of overcoming those issues. By optimising stimulation parameters based on patient profiles, the SR-ML framework uses ML algorithms. This integration will enhance the efficacy and facilitates the customized NIBS therapies. During NIBS sessions, the Time-Series (TS) neural data is analyzed and classified by the application of the Recurrent (NN) Neural Network (RNN). The temporal relationships and patterns indicating neuroplastic variations were effectively identified by this RNN.

Results

The stroke patients neuroplasticity signs was improved, and effective rehabilitation outcomes was attained by the suggested SR-ML model, and it was demonstrated by the outcomes of the simulation. The accuracy and adaptability of NIBS interventions were enhanced by the potential of ML, and it is highlighted by the outcomes.

Conclusion

A revolutionized development in the customized SR was facilitated by the suggested SR-ML framework, as it integrates ML with NIBS. More effective and PC neurotherapeutic approaches was attained by RT classification and optimization of simulation protocols. Thus, the limitations in the current SR methods was addressed by the effective method