Effectiveness of topical application with dexamethasone during sagittal split osteotomy of the mandible in minimising clinical symptoms of postoperative neurosensory disorders.

IF 1.8 3区 医学 Q2 SURGERY BMC Surgery Pub Date : 2025-02-20 DOI:10.1186/s12893-025-02803-1
Iryna Logvynenko, Larysa Dakhno, Valeriia Bursova
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引用次数: 0

Abstract

Background: The aim of this study was to investigate the effectiveness of topical application with dexamethasone during BSSO due to its anti-inflammatory effect and decreasing of postoperative nerve oedema in minimising clinical symptoms of NSD associated with inferior alveolar nerve (IAN) injury in postoperative period, based on the results of sensory diagnostic tests, such as light touch test and its modifications.

Methods: Through randomisation, 2 groups were selected from 22 patients: the experimental- where topical application with solution of dexamethasone phosphate 0.4% (4 mg/1 ml ampules) during sagittal split osteotomy of the mandible was used, and the control- where the classical technique of BSSO was held.

Results: Authors performed diagnostics of NSD using Light Touch test on 1st day, 1st week, 1st month, 3rd month and 6th month postoperatively. The experimental group showed improvements in sensory recovery compared to the control group, particularly from 1 week to 3 months post-surgery. By 6 months, both groups achieved similar levels of sensitivity restoration.

Conclusions: This confirms the effectiveness of proposed method and opens up further prospects for the updated function of the IAN following the BSSO.

Clinical trial number: Not applicable.

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下颌骨矢状面劈开截骨术中局部应用地塞米松减轻术后神经感觉障碍临床症状的效果
背景:本研究的目的是根据轻触试验等感觉诊断试验的结果及其修改,探讨在BSSO期间局部应用地塞米松的抗炎作用和减少术后神经水肿对减轻术后伴有下肺泡神经(IAN)损伤的NSD临床症状的有效性。方法:通过随机分组,从22例患者中选择2组:实验组在下颌骨矢状面劈裂截骨术中局部应用磷酸地塞米松溶液0.4% (4mg / 1ml),对照组采用经典的BSSO技术。结果:作者分别于术后第1天、第1周、第1个月、第3个月、第6个月采用轻触法对NSD进行诊断。与对照组相比,实验组的感觉恢复有所改善,尤其是术后1周到3个月。6个月后,两组患者的敏感性恢复水平相似。结论:这证实了所提出方法的有效性,并为继BSSO之后的IAN更新功能开辟了进一步的前景。临床试验号:不适用。
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来源期刊
BMC Surgery
BMC Surgery SURGERY-
CiteScore
2.90
自引率
5.30%
发文量
391
审稿时长
58 days
期刊介绍: BMC Surgery is an open access, peer-reviewed journal that considers articles on surgical research, training, and practice.
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