The future of cardiovascular magnetic resonance imaging in thoracic aortopathy: blueprint for the paradigm shift to improve management.

IF 6.1 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Journal of Cardiovascular Magnetic Resonance Pub Date : 2025-01-01 Epub Date: 2025-02-21 DOI:10.1016/j.jocmr.2025.101865
James Nadel, José Rodríguez-Palomares, Alkystis Phinikaridou, Claudia Prieto, Pier-Giorgio Masci, René Botnar
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Abstract

Thoracic aortopathies result in aneurysmal expansion of the aorta that can lead to rapidly fatal aortic dissection or rupture. Despite the availability of abundant non-invasive imaging tools, the greatest contemporary challenge in the management of thoracic aortic aneurysm (TAA) is the lack of reliable metrics for risk stratification, with absolute aortic diameter, growth rate, and syndromic factors remaining the primary determinants by which prophylactic surgical intervention is adjudged. Advanced cardiovascular magnetic resonance (CMR) techniques present a potential key to unlocking insights into TAA that could guide disease surveillance and surgical intervention. CMR has the capacity to encapsulate the aorta as a complex biomechanical structure, permitting the determination of aortic volume, morphology, composition, distensibility, and fluid dynamics in a time-efficient manner. Nevertheless, current standard-of-care imaging protocols do not harness its full capacity. This state-of-the-art review explores the emerging role of CMR in the assessment of TAA and presents a blueprint for the required paradigm shift away from aortic size as the sole metric for risk-stratifying TAA.

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MRI在胸主动脉病变中的未来:模式转变以改善管理的蓝图。
胸主动脉病变会导致动脉瘤样的主动脉扩张,从而导致致命的主动脉夹层或破裂。尽管有大量的无创成像工具,但目前胸主动脉瘤(TAA)治疗面临的最大挑战是缺乏可靠的风险分层指标,主动脉绝对直径、生长速度和综合征因素仍然是判断预防性手术干预的主要决定因素。先进的MRI技术是揭示TAA的潜在关键,可以指导疾病监测和手术干预。MRI有能力将主动脉作为一个复杂的生物力学结构包裹起来,允许以一种高效的方式确定主动脉的体积、形态、组成、膨胀性和流体动力学。然而,目前的标准护理成像方案并没有充分利用其能力。这篇最新的综述探讨了MRI在TAA评估中的新兴作用,并提出了所需的范式转变蓝图,不再将主动脉尺寸作为TAA风险分层的唯一指标。
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来源期刊
CiteScore
10.90
自引率
12.50%
发文量
61
审稿时长
6-12 weeks
期刊介绍: Journal of Cardiovascular Magnetic Resonance (JCMR) publishes high-quality articles on all aspects of basic, translational and clinical research on the design, development, manufacture, and evaluation of cardiovascular magnetic resonance (CMR) methods applied to the cardiovascular system. Topical areas include, but are not limited to: New applications of magnetic resonance to improve the diagnostic strategies, risk stratification, characterization and management of diseases affecting the cardiovascular system. New methods to enhance or accelerate image acquisition and data analysis. Results of multicenter, or larger single-center studies that provide insight into the utility of CMR. Basic biological perceptions derived by CMR methods.
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