Acceleration of BNCT dose map calculations via convolutional neural networks

IF 1.8 3区 工程技术 Q3 CHEMISTRY, INORGANIC & NUCLEAR Applied Radiation and Isotopes Pub Date : 2025-02-20 DOI:10.1016/j.apradiso.2025.111718
G. Marzik , M.E. Capoulat , A.J. Kreiner , D.M. Minsky
{"title":"Acceleration of BNCT dose map calculations via convolutional neural networks","authors":"G. Marzik ,&nbsp;M.E. Capoulat ,&nbsp;A.J. Kreiner ,&nbsp;D.M. Minsky","doi":"10.1016/j.apradiso.2025.111718","DOIUrl":null,"url":null,"abstract":"<div><div>A carefully made treatment plan is of paramount importance in order to achieve satisfactory results in treatments based on Boron Neutron Capture Therapy. Different source configurations and positions have to be analyzed, and based on the different dose maps that can be computed, an optimal treatment should be chosen. Nowadays the dose maps are computed using slow and computationally intensive Monte Carlo simulations, which hinder the formulation of an optimized treatment plan. This work proposes a machine learning algorithm based on a convolutional neural network that accelerates the convergence of Monte Carlo neutron transport simulations, drastically reducing computation time without loss of accuracy. A dataset of Monte Carlo simulation was made and used for the training of the proposed model. 97% of the voxels of the set of testing simulations had errors lower than 5% when processed by the neural network, and inference times were reduced by three orders of magnitude. In the future, this tool could allow a real optimization of treatment plans.</div></div>","PeriodicalId":8096,"journal":{"name":"Applied Radiation and Isotopes","volume":"220 ","pages":"Article 111718"},"PeriodicalIF":1.8000,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied Radiation and Isotopes","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0969804325000636","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, INORGANIC & NUCLEAR","Score":null,"Total":0}
引用次数: 0

Abstract

A carefully made treatment plan is of paramount importance in order to achieve satisfactory results in treatments based on Boron Neutron Capture Therapy. Different source configurations and positions have to be analyzed, and based on the different dose maps that can be computed, an optimal treatment should be chosen. Nowadays the dose maps are computed using slow and computationally intensive Monte Carlo simulations, which hinder the formulation of an optimized treatment plan. This work proposes a machine learning algorithm based on a convolutional neural network that accelerates the convergence of Monte Carlo neutron transport simulations, drastically reducing computation time without loss of accuracy. A dataset of Monte Carlo simulation was made and used for the training of the proposed model. 97% of the voxels of the set of testing simulations had errors lower than 5% when processed by the neural network, and inference times were reduced by three orders of magnitude. In the future, this tool could allow a real optimization of treatment plans.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
卷积神经网络加速BNCT剂量图计算
为了在硼中子俘获治疗中取得满意的治疗效果,精心制定的治疗计划是至关重要的。必须分析不同的源配置和位置,并根据可计算的不同剂量图,选择最佳处理方法。目前的剂量图是使用缓慢和计算密集的蒙特卡罗模拟计算的,这阻碍了优化治疗计划的制定。这项工作提出了一种基于卷积神经网络的机器学习算法,该算法加速了蒙特卡罗中子输运模拟的收敛,在不损失精度的情况下大大减少了计算时间。利用蒙特卡罗模拟数据集对所提出的模型进行了训练。经过神经网络处理后,97%的测试模拟体素的误差低于5%,推理时间减少了三个数量级。在未来,这个工具可以实现治疗计划的真正优化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Applied Radiation and Isotopes
Applied Radiation and Isotopes 工程技术-核科学技术
CiteScore
3.00
自引率
12.50%
发文量
406
审稿时长
13.5 months
期刊介绍: Applied Radiation and Isotopes provides a high quality medium for the publication of substantial, original and scientific and technological papers on the development and peaceful application of nuclear, radiation and radionuclide techniques in chemistry, physics, biochemistry, biology, medicine, security, engineering and in the earth, planetary and environmental sciences, all including dosimetry. Nuclear techniques are defined in the broadest sense and both experimental and theoretical papers are welcome. They include the development and use of α- and β-particles, X-rays and γ-rays, neutrons and other nuclear particles and radiations from all sources, including radionuclides, synchrotron sources, cyclotrons and reactors and from the natural environment. The journal aims to publish papers with significance to an international audience, containing substantial novelty and scientific impact. The Editors reserve the rights to reject, with or without external review, papers that do not meet these criteria. Papers dealing with radiation processing, i.e., where radiation is used to bring about a biological, chemical or physical change in a material, should be directed to our sister journal Radiation Physics and Chemistry.
期刊最新文献
Sensitivity gains and quality control in radioxenon monitoring via laboratory Re-measurements Monte Carlo sensitivity analysis of the Vinten 671 ionization chamber activity calibration coefficients Impact of arc therapy in boron neutron capture therapy (BNCT) on dose uniformity and motion robustness The EURAMET.RI(II)-S9 interlaboratory comparison of the radionuclide calibrators Theoretical investigation of alternative 177Lu production methods using proton accelerator: A Monte Carlo study
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1