Predicting mental health disorder onsets with Fibonacci sequencing: A genetic and epigenetic perspective

IF 3.2 2区 医学 Q1 PSYCHIATRY Journal of psychiatric research Pub Date : 2025-03-01 Epub Date: 2025-02-22 DOI:10.1016/j.jpsychires.2025.02.036
Rob G. Sacco , Bernard B. Beitman , Terry Marks-Tarlow
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Abstract

This study explores a novel intersection between molecular biology, genomics, and mathematical modeling to predict the onset patterns of mental health disorders. By investigating the alignment between the Fibonacci sequence and the timing of genetic and epigenetic events, this research seeks to uncover whether these patterns can serve as a predictive model for the onset of disorders such as schizophrenia, bipolar disorder, and major depressive disorder. Leveraging epidemiological data and advanced time-series analysis, the study examines how the temporal progression of molecular markers corresponds to clinical manifestation ages in mental health disorders. Findings indicate that specific ages of disorder onset show significant alignment with Fibonacci harmonics, suggesting a potential natural synchrony within biological processes. This interdisciplinary approach could enhance predictive accuracy, supporting early intervention and personalized mental health strategies, and offering a new perspective on the molecular underpinnings of psychiatric conditions.
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用斐波那契序列预测精神健康障碍的发作:遗传学和表观遗传学的观点
本研究探索了分子生物学、基因组学和数学模型之间的新交叉,以预测精神健康障碍的发病模式。通过研究斐波那契序列与遗传和表观遗传事件时间之间的一致性,本研究试图揭示这些模式是否可以作为精神分裂症、双相情感障碍和重度抑郁症等疾病发病的预测模型。利用流行病学数据和先进的时间序列分析,该研究考察了精神健康障碍患者分子标志物的时间进展如何与临床表现年龄相对应。研究结果表明,疾病发病的特定年龄与斐波那契谐波有显著的一致性,表明生物过程中可能存在自然同步性。这种跨学科的方法可以提高预测的准确性,支持早期干预和个性化的心理健康策略,并为精神疾病的分子基础提供新的视角。
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来源期刊
Journal of psychiatric research
Journal of psychiatric research 医学-精神病学
CiteScore
7.30
自引率
2.10%
发文量
622
审稿时长
130 days
期刊介绍: Founded in 1961 to report on the latest work in psychiatry and cognate disciplines, the Journal of Psychiatric Research is dedicated to innovative and timely studies of four important areas of research: (1) clinical studies of all disciplines relating to psychiatric illness, as well as normal human behaviour, including biochemical, physiological, genetic, environmental, social, psychological and epidemiological factors; (2) basic studies pertaining to psychiatry in such fields as neuropsychopharmacology, neuroendocrinology, electrophysiology, genetics, experimental psychology and epidemiology; (3) the growing application of clinical laboratory techniques in psychiatry, including imagery and spectroscopy of the brain, molecular biology and computer sciences;
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