Alex Wilkinson, Mina Khezrian, Liam G Heaney, Soram Patel, Jennifer K Quint, Hitasha Rupani, Eleni Rapsomaniki, Kirsty Rhodes, Andrew N Menzies-Gow, Trung N Tran
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引用次数: 0
Abstract
Background: The COP28 Declaration on Climate and Health promotes steps to curb emissions and reduce waste in the health sector.
Objective: To describe and quantify greenhouse gas (GHG) emissions associated with severe asthma (SA) care in the UK, by carbon source and transition status from SA to severe uncontrolled asthma (SUA) and/or regular specialist care (RSC).
Methods: This was a cohort study using routinely collected data from the Clinical Practice Research Datalink Aurum, Hospital Episode Statistics and CO2 equivalent emissions data. Patients were ≥12 years old at index date (i.e. date of first recorded ICS + controller prescription) with a validated asthma diagnosis. Total-, medication-, exacerbation- and healthcare resource utilisation (HCRU)-related GHG emissions were estimated, overall and by transition along stages of the SA-SUA-RSC continuum. Five pathways and stage orders were identified: 1. SA, 2. SA-SUA, 3. SA-RSC, 4. SA-RSC-SUA, 5. SA-SUA-RSC.
Results: Total CO2 eq for the SA population (n=93,054) was 2167 tonnes/10K patients/year. GHG emissions were 5.2-23.0% greater for patients transitioned to SUA (versus previous stage), mostly due to exacerbation-related emissions (4.2-7.7 times greater; predominantly hospitalizations) and medication-related emissions (3.5-10.9% greater; predominantly SABAs). Conversely, total GHG emissions decreased by 12.1-23.9% for those referred to RSC, due to decreased exacerbation-related emissions (1.7-5.2 times lower; all sources) and medication-related emissions (14.8-20.6% lower; both SABA and overall ICS).
Conclusion: Our findings suggest that RSC not only improves patient outcomes but also reduces GHG emissions in line with aims to reduce the health sector's contribution to the total national carbon footprint.
期刊介绍:
JACI: In Practice is an official publication of the American Academy of Allergy, Asthma & Immunology (AAAAI). It is a companion title to The Journal of Allergy and Clinical Immunology, and it aims to provide timely clinical papers, case reports, and management recommendations to clinical allergists and other physicians dealing with allergic and immunologic diseases in their practice. The mission of JACI: In Practice is to offer valid and impactful information that supports evidence-based clinical decisions in the diagnosis and management of asthma, allergies, immunologic conditions, and related diseases.
This journal publishes articles on various conditions treated by allergist-immunologists, including food allergy, respiratory disorders (such as asthma, rhinitis, nasal polyps, sinusitis, cough, ABPA, and hypersensitivity pneumonitis), drug allergy, insect sting allergy, anaphylaxis, dermatologic disorders (such as atopic dermatitis, contact dermatitis, urticaria, angioedema, and HAE), immunodeficiency, autoinflammatory syndromes, eosinophilic disorders, and mast cell disorders.
The focus of the journal is on providing cutting-edge clinical information that practitioners can use in their everyday practice or to acquire new knowledge and skills for the benefit of their patients. However, mechanistic or translational studies without immediate or near future clinical relevance, as well as animal studies, are not within the scope of the journal.