Hearing loss assessment by pure tone audiometry amongst the survivors of intensive care unit: A prospective observational cohort study

IF 2.9 3区医学 Q2 CRITICAL CARE MEDICINE Journal of critical care Pub Date : 2025-02-26 DOI:10.1016/j.jcrc.2025.155042

Sai Saran , Abhishek Bahadur Singh , Avinash Agrawal , Saumitra Misra , Suhail Sarwar Siddiqui , Ayush Lohiya , Prabhaker Misra

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Abstract

Purpose

To assess hearing deficits (HD) through pure tone audiometry (PTA), amongst the survivors of intensive care unit (ICU).

Methods

In this prospective observational study, ICU survivors aged 18 years and above were subjected to PTA and were classified into two groups based on PTA findings as those “with HD” and “without HD”. Demographic and clinical factors were compared between these groups with a p-value of ≤0.05 considered as significant.

Results

One hundred and two survivors were enrolled with a median age of 25.5 years (23–30.5), and acute physiology and chronic health evaluation (APACHE II) score of 19 (14–22). Sixty were diagnosed (58.89 %) with HD based on PTA, and forty-two (41.2 %) without HD. More than 80 % of the survivors (52/60) had sensorineural hearing loss (SNHL). Propensity match analysis, after the exact matching of the APACHE-II score between those “with HD” and “without HD”, revealed that patients with HD had a longer duration of shock days (mean ± SD) (0.96 ± 1.24 vs 1.68 ± 1.28; p value: 0.022), received higher maximum noradrenaline dose (0.03 v/s 0.06 μg/kg/min; p value: 0.004), longer duration of endotracheal tube (2.04 ± 1.17 vs 3.52 ± 2.06) days; p value:0.009), more days on mechanical ventilation (2.24 ± 1.33 vs 4.44 ± 5.12; p value: 0.011), and length of stay in the ICU (7.2 ± 3.8 vs 9.24 ± 4.68; p value: 0.013) than those without HD.

Conclusions

Hearing deficits are present in majority of the survivors of critical illness and audiometric screening is recommended.

Trial Registration: Clinical trials registry. India (CTRI/2022/01/039539) dated 18.01.2022. https://ctri.nic.in/Clinicaltrials/login.php

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重症监护病房幸存者的纯音听力损失评估：一项前瞻性观察队列研究

目的通过纯音听力学（PTA）评估重症监护病房（ICU）幸存者的听力缺陷（HD）。方法在这项前瞻性观察性研究中，18岁及以上的ICU幸存者接受PTA治疗，并根据PTA结果将其分为“患有HD”和“未患有HD”两组。组间人口学及临床因素比较，p值≤0.05为差异有统计学意义。结果纳入102例幸存者，中位年龄25.5岁（23-30.5岁），急性生理和慢性健康评估（APACHE II）评分19分（14-22分）。60例（58.89%）经PTA诊断为HD， 42例（41.2%）未诊断为HD。超过80%的幸存者（52/60）患有感音神经性听力损失（SNHL）。倾向匹配分析显示，在“有HD”和“没有HD”患者的APACHE-II评分精确匹配后，HD患者的休克天数更长（平均±SD）（0.96±1.24 vs 1.68±1.28）；P值：0.022)，最大去甲肾上腺素剂量为0.03 v/s, 0.06 μg/kg/min；P值：0.004)，气管插管时间较长（2.04±1.17 vs 3.52±2.06）天；P值：0.009)，机械通气天数较多(2.24±1.33 vs 4.44±5.12；p值：0.011)，ICU住院时间(7.2±3.8 vs 9.24±4.68；p值：0.013)。结论大多数危重疾病幸存者存在听力缺陷，建议进行听力筛查。试验注册：临床试验注册。印度（CTRI/2022/01/039539），日期为2022年1月18日。https://ctri.nic.in/Clinicaltrials/login.php

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来源期刊

Journal of critical care 医学-危重病医学

CiteScore

8.60

自引率

2.70%

发文量

237

审稿时长

23 days

期刊介绍： The Journal of Critical Care, the official publication of the World Federation of Societies of Intensive and Critical Care Medicine (WFSICCM), is a leading international, peer-reviewed journal providing original research, review articles, tutorials, and invited articles for physicians and allied health professionals involved in treating the critically ill. The Journal aims to improve patient care by furthering understanding of health systems research and its integration into clinical practice. The Journal will include articles which discuss: All aspects of health services research in critical care System based practice in anesthesiology, perioperative and critical care medicine The interface between anesthesiology, critical care medicine and pain Integrating intraoperative management in preparation for postoperative critical care management and recovery Optimizing patient management, i.e., exploring the interface between evidence-based principles or clinical insight into management and care of complex patients The team approach in the OR and ICU System-based research Medical ethics Technology in medicine Seminars discussing current, state of the art, and sometimes controversial topics in anesthesiology, critical care medicine, and professional education Residency Education.