Randomized Clinical Study of Laser vs. Cryotherapy in Plantar Warts: Effectiveness and Safety

IF 3.7 4区医学 Q1 DERMATOLOGY Dermatologic Therapy Pub Date : 2025-02-25 DOI:10.1155/dth/7793571

Giuliana Secolo, Innocenzo Salvatore Secolo, Nadia Fernández-Ehrling, Juan Vicente-Mampel, Raul Gallego-Estévez, Javier Ferrer-Torregrosa

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Abstract

Introduction: Plantar warts are common skin lesions caused by HPV that can generate discomfort and impact quality of life. There are several therapeutic options such as cryotherapy or laser, but more high-quality comparative studies are needed.

Methods: A randomized clinical trial was performed with 44 patients with plantar warts who were assigned 22 to each group. Sessions were applied at 1-week intervals evaluating clinical healing, VAS pain scale, and complications.

Results: Laser removed warts in significantly fewer sessions (mean 3.26) than cryotherapy (mean 4.06) (p = 0.022). There were no differences in safety or pain between groups.

Conclusion: Diode laser demonstrated faster removal of plantar warts than cryotherapy, constituting a promising noninvasive alternative. Further studies are needed to confirm its long-term efficacy and safety profile.

Trial Registration: ClinicalTrials.gov identifier: NCT06228521

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来源期刊

Dermatologic Therapy 医学-皮肤病学

CiteScore

7.00

自引率

8.30%

发文量

711

审稿时长

3 months

期刊介绍： Dermatologic Therapy has been created to fill an important void in the dermatologic literature: the lack of a readily available source of up-to-date information on the treatment of specific cutaneous diseases and the practical application of specific treatment modalities. Each issue of the journal consists of a series of scholarly review articles written by leaders in dermatology in which they describe, in very specific terms, how they treat particular cutaneous diseases and how they use specific therapeutic agents. The information contained in each issue is so practical and detailed that the reader should be able to directly apply various treatment approaches to daily clinical situations. Because of the specific and practical nature of this publication, Dermatologic Therapy not only serves as a readily available resource for the day-to-day treatment of patients, but also as an evolving therapeutic textbook for the treatment of dermatologic diseases.