Influence of Processing Parameters on Additively Manufactured Architected Cellular Metals: Emphasis on Biomedical Applications.

IF 5.2 3区 医学 Q1 ENGINEERING, BIOMEDICAL Journal of Functional Biomaterials Pub Date : 2025-02-08 DOI:10.3390/jfb16020053
Yixuan Shi, Yuzhe Zheng, Chengcong Huang, Shangyan Zhao, Xuan Li, Yuchen Lu, Yuzhi Wu, Peipei Li, Luning Wang, Yageng Li
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Abstract

Laser powder bed fusion (LPBF) has emerged as a transformative additive manufacturing technique for fabricating architected cellular metallic structures, offering tailored properties for diverse biomedical applications. These structures are particularly well-suited for bone implants, scaffolds, and other load-bearing medical devices due to their ability to achieve lightweight designs, enhanced mechanical properties, and customized geometries. However, the complex interactions between LPBF process parameters and the resulting structural and mechanical properties pose significant challenges in achieving the precision and reliability required for clinical applications. This review provides a comprehensive analysis of the effects of LPBF process parameters, including laser power, scanning speed, and layer thickness, on key attributes such as dimensional accuracy, density, surface roughness, and microstructure. Their influence on the mechanical performance, including strength, fatigue resistance, and functional properties, is critically examined, with specific attention to biomedical relevance. The impact of lattice design factors, such as topology, unit cell size, and orientation, is also discussed, underscoring their role in optimizing biocompatibility and structural integrity for medical applications. Challenges such as surface defects, geometric inaccuracies, and microstructural inconsistencies are highlighted as key barriers to the broader adoption of LPBF in biomedical fields. Future perspectives focus on advancing LPBF technologies through process optimization and integration with advanced computational tools, such as machine learning, to enable efficient manufacturing of complex, patient-specific architectures. By addressing these challenges, LPBF has the potential to revolutionize the development of next-generation biomaterials, tailored to meet evolving clinical needs and improve patient outcomes.

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加工参数对增材制造结构细胞金属的影响:重点是生物医学应用。
激光粉末床融合(LPBF)已经成为一种变革性的增材制造技术,用于制造有结构的细胞金属结构,为各种生物医学应用提供量身定制的性能。这些结构特别适合于骨植入物、支架和其他承重医疗设备,因为它们能够实现轻量化设计、增强机械性能和定制几何形状。然而,LPBF工艺参数与产生的结构和机械性能之间复杂的相互作用对实现临床应用所需的精度和可靠性提出了重大挑战。本文全面分析了激光功率、扫描速度、层厚等LPBF工艺参数对尺寸精度、密度、表面粗糙度和微观结构等关键属性的影响。它们对机械性能的影响,包括强度、抗疲劳性和功能特性,是严格审查的,特别关注生物医学的相关性。晶格设计因素的影响,如拓扑,单位细胞大小和方向,也进行了讨论,强调他们在优化生物相容性和医疗应用结构完整性的作用。诸如表面缺陷、几何不精确和微观结构不一致等挑战被强调为LPBF在生物医学领域广泛采用的主要障碍。未来的前景将集中在通过流程优化和与先进计算工具(如机器学习)的集成来推进LPBF技术,以实现复杂的、特定于患者的架构的高效制造。通过解决这些挑战,LPBF有可能彻底改变下一代生物材料的发展,以满足不断变化的临床需求并改善患者的治疗效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Functional Biomaterials
Journal of Functional Biomaterials Engineering-Biomedical Engineering
CiteScore
4.60
自引率
4.20%
发文量
226
审稿时长
11 weeks
期刊介绍: Journal of Functional Biomaterials (JFB, ISSN 2079-4983) is an international and interdisciplinary scientific journal that publishes regular research papers (articles), reviews and short communications about applications of materials for biomedical use. JFB covers subjects from chemistry, pharmacy, biology, physics over to engineering. The journal focuses on the preparation, performance and use of functional biomaterials in biomedical devices and their behaviour in physiological environments. Our aim is to encourage scientists to publish their results in as much detail as possible. Therefore, there is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Several topical special issues will be published. Scope: adhesion, adsorption, biocompatibility, biohybrid materials, bio-inert materials, biomaterials, biomedical devices, biomimetic materials, bone repair, cardiovascular devices, ceramics, composite materials, dental implants, dental materials, drug delivery systems, functional biopolymers, glasses, hyper branched polymers, molecularly imprinted polymers (MIPs), nanomedicine, nanoparticles, nanotechnology, natural materials, self-assembly smart materials, stimuli responsive materials, surface modification, tissue devices, tissue engineering, tissue-derived materials, urological devices.
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