{"title":"Laser-Induced Spatially Controlled Microbubble Formation in Trithiocyanuric Acid-Based Capsules Modified with Gold Nanoparticles","authors":"O. O. Peltek, E. A. Kopoleva, M. V. Zyuzin","doi":"10.1134/S1062873824710043","DOIUrl":null,"url":null,"abstract":"<p>Microbubbles have numerous applications in fields such as drug delivery, diagnostic imaging, and localized therapies. In this study, we propose a method for generating microbubbles with controlled size, confined by the dimensions of a hollow shell. The hollow capsules were fabricated from trithiocyanuric acid and further modified with gold nanoparticles to enhance their photothermal properties. We demonstrate that irradiation with a near-infrared laser can induce the formation of microbubbles within these capsules. The bubbles remain spatially confined by the shell and stable for the duration of the laser operation. This approach offers a versatile platform for applications requiring targeted control of microbubble formation and heat generation in biomedical and microfluidic systems.</p>","PeriodicalId":504,"journal":{"name":"Bulletin of the Russian Academy of Sciences: Physics","volume":"88 3 supplement","pages":"S472 - S475"},"PeriodicalIF":0.4800,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bulletin of the Russian Academy of Sciences: Physics","FirstCategoryId":"1085","ListUrlMain":"https://link.springer.com/article/10.1134/S1062873824710043","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Physics and Astronomy","Score":null,"Total":0}
引用次数: 0
Abstract
Microbubbles have numerous applications in fields such as drug delivery, diagnostic imaging, and localized therapies. In this study, we propose a method for generating microbubbles with controlled size, confined by the dimensions of a hollow shell. The hollow capsules were fabricated from trithiocyanuric acid and further modified with gold nanoparticles to enhance their photothermal properties. We demonstrate that irradiation with a near-infrared laser can induce the formation of microbubbles within these capsules. The bubbles remain spatially confined by the shell and stable for the duration of the laser operation. This approach offers a versatile platform for applications requiring targeted control of microbubble formation and heat generation in biomedical and microfluidic systems.
期刊介绍：
Bulletin of the Russian Academy of Sciences: Physics is an international peer reviewed journal published with the participation of the Russian Academy of Sciences. It presents full-text articles (regular, letters to the editor, reviews) with the most recent results in miscellaneous fields of physics and astronomy: nuclear physics, cosmic rays, condensed matter physics, plasma physics, optics and photonics, nanotechnologies, solar and astrophysics, physical applications in material sciences, life sciences, etc. Bulletin of the Russian Academy of Sciences: Physics focuses on the most relevant multidisciplinary topics in natural sciences, both fundamental and applied. Manuscripts can be submitted in Russian and English languages and are subject to peer review. Accepted articles are usually combined in thematic issues on certain topics according to the journal editorial policy. Authors featured in the journal represent renowned scientific laboratories and institutes from different countries, including large international collaborations. There are globally recognized researchers among the authors: Nobel laureates and recipients of other awards, and members of national academies of sciences and international scientific societies.
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