The combination of fatigue with the serum GCSF improves the performance of serological screening for frailty.

IF 3.4 2区 生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY Acta biochimica et biophysica Sinica Pub Date : 2025-02-25 DOI:10.3724/abbs.2025007
Jiaming Yu, Jie Chen, Xueying Ji, Yixuan Qiu, Yan Zhang, Jiaofeng Wang, Xiangqi Li, Chaobao Zhang, Zhijun Bao
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Abstract

Frailty is a critical cause leading to elderly death. No drug is available to treat it, while prevention works. However, reliable blood screening and diagnostic methods for frailty are still lacking. Here, we show that the serum GCSF, in combination with the fatigue factor of the frailty scale, can improve the performance of serological screening for frailty.

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疲劳与血清GCSF的结合提高了虚弱的血清学筛查的性能。
虚弱是导致老年人死亡的一个重要原因。没有药物可以治疗它,但预防是有效的。然而,可靠的血液筛查和虚弱的诊断方法仍然缺乏。在这里,我们发现血清GCSF结合虚弱量表的疲劳因子可以提高虚弱的血清学筛查的性能。
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来源期刊
Acta biochimica et biophysica Sinica
Acta biochimica et biophysica Sinica 生物-生化与分子生物学
CiteScore
5.00
自引率
5.40%
发文量
170
审稿时长
3 months
期刊介绍: Acta Biochimica et Biophysica Sinica (ABBS) is an internationally peer-reviewed journal sponsored by the Shanghai Institute of Biochemistry and Cell Biology (CAS). ABBS aims to publish original research articles and review articles in diverse fields of biochemical research including Protein Science, Nucleic Acids, Molecular Biology, Cell Biology, Biophysics, Immunology, and Signal Transduction, etc.
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