Numerical Simulation of the Effect of Electrical Stimulation on Disuse After Hip Replacement.

IF 3.9 3区 工程技术 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY Biomedicines Pub Date : 2025-02-14 DOI:10.3390/biomedicines13020471
Qian Wang, Chuanyong Qu, Xiaohui Li, Yufan Yan
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Abstract

Background: Total hip replacement replaces the femoral head, which cannot heal, with an artificial femoral shaft to ensure the patient's normal life. However, due to the stress-masking effect of the proximal femur loaded with the artificial femur stem, the implant bears a large part of the load, resulting in insufficient stress stimulation of the proximal femur and bone waste remodeling. In turn, it is easy to lose bone, resulting in loosening. As a new treatment method, electrical stimulation has been widely used for bone loss, nonunion, and other diseases, and it has achieved good therapeutic effects. Methods: Therefore, in this work, electrical stimulation was introduced for postoperative density assessment, and a new disuse remodeling model was established to simulate density loss after remodeling and the resistance effect of electrical stimulation. The effects of various parameters on density loss in the model are discussed. Results: The simulation results revealed significant stress masking and density loss in the neck of the femur after hip replacement, and electrical stimulation placed in the neck of the femur may resist this density loss to a certain extent. The rate of bone mineral density reduction decreased after the addition of electrical stimulation, indicating that electrical stimulation can have a certain resistance to the density reduction caused by stress shielding, and this result is helpful for the rehabilitation of hip arthroplasty.

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电刺激对髋关节置换术后废用影响的数值模拟。
背景:全髋关节置换术用人工股骨干代替不能愈合的股骨头,保证患者的正常生活。然而,由于股骨近端负载人工股骨干的应力掩盖效应,植入物承担了很大一部分负荷,导致股骨近端应力刺激不足,骨废物重塑。反过来,很容易骨质流失,导致松动。电刺激作为一种新的治疗方法,已广泛应用于骨质疏松、骨不连等疾病,并取得了良好的治疗效果。方法:因此,本工作引入电刺激进行术后密度评估,并建立新的废用重构模型,模拟重构后密度损失和电刺激的阻力效应。讨论了模型中各参数对密度损失的影响。结果:模拟结果显示,髋关节置换术后股骨颈部存在明显的应力掩蔽和密度损失,在股骨颈部进行电刺激可以在一定程度上抵抗这种密度损失。增加电刺激后骨密度降低率下降,说明电刺激对应力屏蔽引起的密度降低有一定的抵抗作用,这一结果对髋关节置换术后的康复有帮助。
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来源期刊
Biomedicines
Biomedicines Biochemistry, Genetics and Molecular Biology-General Biochemistry,Genetics and Molecular Biology
CiteScore
5.20
自引率
8.50%
发文量
2823
审稿时长
8 weeks
期刊介绍: Biomedicines (ISSN 2227-9059; CODEN: BIOMID) is an international, scientific, open access journal on biomedicines published quarterly online by MDPI.
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