Three-Month Durability of Bilateral Two-Level Stellate Ganglion Blocks in Patients with Generalized Anxiety Disorder: A Retrospective Analysis.

IF 2.8 3区医学 Q3 NEUROSCIENCES Brain Sciences Pub Date : 2025-02-13 DOI:10.3390/brainsci15020188

Sean W Mulvaney, Kyle J Dineen, Sanjay Mahadevan, Roosevelt Desronvilles, Kristine L Rae Olmsted

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Abstract

Purpose: Determine if performing ultrasound-guided, bilateral, two-level cervical sympathetic chain blocks (2LCSB) (performed on subsequent days) provides durable improvement in symptoms associated with anxiety. Methods: A retrospective chart review was conducted between January 2022 and November 2024. We identified 114 patients who received bilateral, 2LCSB for anxiety symptoms. Generalized Anxiety Disorder 7-Item Scale (GAD-7) outcome measure scores were collected at baseline and three-months post procedure in 71 males and 43 females. Results: Out of 114 patients, 99 patients (86.8%) showed a long-lasting improvement in their GAD-7 scores. Collected GAD-7 forms had a baseline average of 15.52 (14.99 for males and 16.40 for females), which decreased after three months to an average of 7.28 (6.96 for males and 7.81 for females). This represents a 52% average improvement in anxiety symptoms. Conclusions: In individuals treated with bilateral, 2LCSB, GAD-related symptoms were improved by 52% for at least 3 months regardless of initial anxiety severity.

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广泛性焦虑障碍患者双侧双水平星状神经节阻滞三个月的持久性：回顾性分析。

目的：确定超声引导、双侧、两级颈交感神经链阻滞（2LCSB）（在随后几天进行）是否能持久改善焦虑相关症状。方法：对2022年1月至2024年11月的病例进行回顾性分析。我们确定了114例因焦虑症状接受双侧lcsb治疗的患者。在基线和手术后3个月收集了71名男性和43名女性的广泛性焦虑障碍7项量表（GAD-7）结果测量评分。结果：114例患者中，99例（86.8%）患者的GAD-7评分出现持久改善。收集到的GAD-7表格的基线平均值为15.52（男性为14.99，女性为16.40），三个月后下降到平均7.28（男性为6.96，女性为7.81）。这意味着焦虑症状平均改善了52%。结论：在双侧、双侧lcsb治疗的个体中，无论最初的焦虑严重程度如何，gad相关症状在至少3个月内改善了52%。

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来源期刊

Brain Sciences Neuroscience-General Neuroscience

CiteScore

4.80

自引率

9.10%

发文量

1472

审稿时长

18.71 days

期刊介绍： Brain Sciences (ISSN 2076-3425) is a peer-reviewed scientific journal that publishes original articles, critical reviews, research notes and short communications in the areas of cognitive neuroscience, developmental neuroscience, molecular and cellular neuroscience, neural engineering, neuroimaging, neurolinguistics, neuropathy, systems neuroscience, and theoretical and computational neuroscience. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Electronic files or software regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material.