{"title":"So Close, and Yet… Plasma HPV DNA Detection of Recurrent HPV Oropharynx Cancer.","authors":"Joseph A Califano","doi":"10.1158/1078-0432.CCR-25-0012","DOIUrl":null,"url":null,"abstract":"<p><p>Plasma human papilloma virus (HPV) DNA is a biomarker closely associated with HPV-mediated oropharynx cancer recurrence. This CCR Translations discusses the potential utility of plasma HPV DNA in predicting HPV oropharynx cancer recurrence, and the challenges of application to clinical practice.</p>","PeriodicalId":10279,"journal":{"name":"Clinical Cancer Research","volume":" ","pages":""},"PeriodicalIF":10.0000,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Cancer Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1158/1078-0432.CCR-25-0012","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Plasma human papilloma virus (HPV) DNA is a biomarker closely associated with HPV-mediated oropharynx cancer recurrence. This CCR Translations discusses the potential utility of plasma HPV DNA in predicting HPV oropharynx cancer recurrence, and the challenges of application to clinical practice.
期刊介绍:
Clinical Cancer Research is a journal focusing on groundbreaking research in cancer, specifically in the areas where the laboratory and the clinic intersect. Our primary interest lies in clinical trials that investigate novel treatments, accompanied by research on pharmacology, molecular alterations, and biomarkers that can predict response or resistance to these treatments. Furthermore, we prioritize laboratory and animal studies that explore new drugs and targeted agents with the potential to advance to clinical trials. We also encourage research on targetable mechanisms of cancer development, progression, and metastasis.