Gels as Promising Delivery Systems: Physicochemical Property Characterization and Recent Applications.

IF 5.5 3区医学 Q1 PHARMACOLOGY & PHARMACY Pharmaceutics Pub Date : 2025-02-14 DOI:10.3390/pharmaceutics17020249

Enzhao Wang, Zhaoying Qi, Yuzhou Cao, Ruixiang Li, Jing Wu, Rongshuang Tang, Yi Gao, Ruofei Du, Minchen Liu

{"title":"Gels as Promising Delivery Systems: Physicochemical Property Characterization and Recent Applications.","authors":"Enzhao Wang, Zhaoying Qi, Yuzhou Cao, Ruixiang Li, Jing Wu, Rongshuang Tang, Yi Gao, Ruofei Du, Minchen Liu","doi":"10.3390/pharmaceutics17020249","DOIUrl":null,"url":null,"abstract":"<p><p>Gels constitute a versatile class of materials with considerable potential for applications in both technical and medical domains. Physicochemical property characterization is a critical evaluation method for gels. Common characterization techniques include pH measurement, structural analysis, mechanical property assessment, rheological analysis, and phase transition studies, among others. While numerous research articles report characterization results, few reviews comprehensively summarize the appropriate numerical ranges for these properties. This lack of standardization complicates harmonized evaluation methods and hinders direct comparisons between different gels. To address this gap, it is essential to systematically investigate characterization methods and analyze data from the extensive body of literature on gels. In this review, we provide a comprehensive summary of general characterization methods and present a detailed analysis of gel characterization data to support future research and promote standardized evaluation protocols.</p>","PeriodicalId":19894,"journal":{"name":"Pharmaceutics","volume":"17 2","pages":""},"PeriodicalIF":5.5000,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11858892/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pharmaceutics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3390/pharmaceutics17020249","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}

引用次数: 0

Abstract

Gels constitute a versatile class of materials with considerable potential for applications in both technical and medical domains. Physicochemical property characterization is a critical evaluation method for gels. Common characterization techniques include pH measurement, structural analysis, mechanical property assessment, rheological analysis, and phase transition studies, among others. While numerous research articles report characterization results, few reviews comprehensively summarize the appropriate numerical ranges for these properties. This lack of standardization complicates harmonized evaluation methods and hinders direct comparisons between different gels. To address this gap, it is essential to systematically investigate characterization methods and analyze data from the extensive body of literature on gels. In this review, we provide a comprehensive summary of general characterization methods and present a detailed analysis of gel characterization data to support future research and promote standardized evaluation protocols.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

凝胶作为有前途的输送系统：物理化学性质表征和最新应用。

凝胶是一种用途广泛的材料，在技术和医疗领域都具有相当大的应用潜力。理化性质表征是凝胶评价的重要方法。常用的表征技术包括pH测量、结构分析、力学性能评估、流变分析和相变研究等。虽然许多研究文章报告了表征结果，但很少有评论全面总结了这些性质的适当数值范围。这种标准化的缺乏使统一的评价方法复杂化，并阻碍了不同凝胶之间的直接比较。为了解决这一差距，系统地研究表征方法和分析大量关于凝胶的文献数据至关重要。在这篇综述中，我们全面总结了常用的表征方法，并对凝胶表征数据进行了详细的分析，以支持未来的研究和促进标准化的评价方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Pharmaceutics Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science

CiteScore

7.90

自引率

11.10%

发文量

2379

审稿时长

16.41 days

期刊介绍： Pharmaceutics (ISSN 1999-4923) is an open access journal which provides an advanced forum for the science and technology of pharmaceutics and biopharmaceutics. It publishes reviews, regular research papers, communications, and short notes. Covered topics include pharmacokinetics, toxicokinetics, pharmacodynamics, pharmacogenetics and pharmacogenomics, and pharmaceutical formulation. Our aim is to encourage scientists to publish their experimental and theoretical details in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced.