Microencapsulation of Probiotics for Enhanced Stability and Health Benefits in Dairy Functional Foods: A Focus on Pasta Filata Cheese.

IF 5.5 3区 医学 Q1 PHARMACOLOGY & PHARMACY Pharmaceutics Pub Date : 2025-02-02 DOI:10.3390/pharmaceutics17020185
Vita D'Amico, Mariasimona Cavaliere, Marianna Ivone, Chiara Lacassia, Giuseppe Celano, Mirco Vacca, Flavia Maria la Forgia, Sergio Fontana, Maria De Angelis, Nunzio Denora, Angela Assunta Lopedota
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Abstract

Probiotics provide significant health benefits, but their viability is often compromised during production, storage, and passage through the gastrointestinal tract. These challenges hinder their effective incorporation into functional applications, particularly in dairy functional foods, in which factors such as acidity, oxygen exposure, and storage conditions negatively impact cell survival. The focus was on functional dairy foods, particularly on pasta filata cheeses. Indeed, the use of probiotics in pasta filata cheeses presents significant challenges due to the specific manufacturing processes, which encompass the application of high temperatures and other harsh conditions. These factors can adversely affect the viability and availability of probiotic microorganisms. However, microencapsulation has emerged as a promising solution, offering a protective barrier that enhances probiotic stability, improves survival rates, and facilitates targeted release in the gastrointestinal environment. This review examines the pivotal role of microencapsulation in stabilising probiotics for functional applications, emphasising its relevance in high-value food systems. Functional applications, including foods designed to offer essential nutritional benefits and promote host health, play a crucial role in disease prevention and immune system support, reducing the risk of infections and other physiological impairments. Key microencapsulation technologies are analysed, focusing on their benefits, limitations, and challenges related to scalability and industrial implementation. Additionally, this review discusses strategies to optimise formulations, ensure the sensory quality of final products, and explore future opportunities for expanding innovative applications that align with growing consumer demand for health-promoting solutions.

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微胶囊化益生菌增强乳制品功能食品的稳定性和健康益处:以意大利面丝状奶酪为重点。
益生菌对健康有益,但在生产、储存和通过胃肠道的过程中,益生菌的生存能力往往受到损害。这些挑战阻碍了它们有效地融入功能性应用,特别是在乳制品功能食品中,其中酸度、氧气暴露和储存条件等因素对细胞存活产生负面影响。研究的重点是功能性乳制品,尤其是意大利面食和奶酪。事实上,由于特定的制造过程,包括高温和其他恶劣条件的应用,在意大利丝奶酪中使用益生菌面临着重大挑战。这些因素会对益生菌微生物的生存能力和可利用性产生不利影响。然而,微胶囊化已经成为一种很有前途的解决方案,它提供了一种保护屏障,可以增强益生菌的稳定性,提高存活率,并促进在胃肠道环境中的靶向释放。这篇综述探讨了微胶囊在功能应用中稳定益生菌的关键作用,强调了其在高价值食品系统中的相关性。功能性应用,包括旨在提供基本营养益处和促进宿主健康的食品,在疾病预防和免疫系统支持、降低感染风险和其他生理损伤方面发挥着至关重要的作用。分析了关键的微封装技术,重点关注它们的优点、局限性以及与可扩展性和工业实现相关的挑战。此外,本文还讨论了优化配方、确保最终产品感官质量的策略,并探讨了扩大创新应用的未来机会,以满足消费者对促进健康解决方案日益增长的需求。
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来源期刊
Pharmaceutics
Pharmaceutics Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science
CiteScore
7.90
自引率
11.10%
发文量
2379
审稿时长
16.41 days
期刊介绍: Pharmaceutics (ISSN 1999-4923) is an open access journal which provides an advanced forum for the science and technology of pharmaceutics and biopharmaceutics. It publishes reviews, regular research papers, communications,  and short notes. Covered topics include pharmacokinetics, toxicokinetics, pharmacodynamics, pharmacogenetics and pharmacogenomics, and pharmaceutical formulation. Our aim is to encourage scientists to publish their experimental and theoretical details in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced.
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