A Meta-Analysis to Assess the Probable Association of Hypertension During Pregnancy and Placenta Accreta.

Abstract

Background and Objectives: A meta-analysis was conducted to assess the probable association of hypertension during pregnancy and placenta accreta (PA). Materials and Methods: A systematic literature search was conducted up to November 2024, resulting in the identification of 10 studies encompassing 128,589 pregnant women. They reported associations between the possible impacts of hypertension during pregnancy and PA. The odds ratio (OR), with 95% confidence intervals (CIs), was computed to evaluate the possible association of hypertension during pregnancy and PA, utilizing a dichotomous approach with either a random or fixed-effect model. Results: No significant difference was found between hypertension during pregnancy and control (no hypertension during pregnancy) in the occurrence of PA (OR, 0.74; 95% CI, 0.52-1.04, p = 0.08). Also, no significant difference was found between pregnant women with PA and control (no PA) in the occurrence of hypertension (OR, 1.15; 95% CI, 0.61-2.19, p = 0.66). Conclusions: Hypertension during pregnancy has no impact on the occurrence of PA, and vice versa. More research is desired to approve these outcomes.