Ervan Salvi, Roméric Galéa, Camille Van Wesemael, Patrick Wagner, Nicolas Girard, Gaëlle Blond
{"title":"Orthogonal Tandem Catalysis involving Au(I)-Hydroacyloxylation and Rh(I)-Hydroformylation reactions","authors":"Ervan Salvi, Roméric Galéa, Camille Van Wesemael, Patrick Wagner, Nicolas Girard, Gaëlle Blond","doi":"10.1039/d5qo00084j","DOIUrl":null,"url":null,"abstract":"We report an Orthogonal Tandem Catalysis (OTC) involving Au(I)-hydroacyloxylation and Rh(I)-hydroformylation highlighting their compatibility when these metals are employed in a reaction of homogeneous catalysis. Moreover, this OTC allows the synthesis of different carbaldehydes. Several derivatizations were performed at the end of the OTC procedure, giving access to two series of alcohol and oxime derivatives. 31P NMR experiments and kinetic studies, carried out on the OTC allowed a detailed understanding of the catalytic cycles involved, highlighting the ligand exchange between the gold and rhodium catalysts.","PeriodicalId":97,"journal":{"name":"Organic Chemistry Frontiers","volume":"26 1","pages":""},"PeriodicalIF":4.6000,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Organic Chemistry Frontiers","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1039/d5qo00084j","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
We report an Orthogonal Tandem Catalysis (OTC) involving Au(I)-hydroacyloxylation and Rh(I)-hydroformylation highlighting their compatibility when these metals are employed in a reaction of homogeneous catalysis. Moreover, this OTC allows the synthesis of different carbaldehydes. Several derivatizations were performed at the end of the OTC procedure, giving access to two series of alcohol and oxime derivatives. 31P NMR experiments and kinetic studies, carried out on the OTC allowed a detailed understanding of the catalytic cycles involved, highlighting the ligand exchange between the gold and rhodium catalysts.
期刊介绍：
Organic Chemistry Frontiers is an esteemed journal that publishes high-quality research across the field of organic chemistry. It places a significant emphasis on studies that contribute substantially to the field by introducing new or significantly improved protocols and methodologies. The journal covers a wide array of topics which include, but are not limited to, organic synthesis, the development of synthetic methodologies, catalysis, natural products, functional organic materials, supramolecular and macromolecular chemistry, as well as physical and computational organic chemistry.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
