Challenges in diagnosing primary tubercular chorioretinitis and ocular tuberculosis in resource-limited settings of Bangladesh

Abstract

Tuberculosis is a pressing global health concern that affects not only the respiratory system but also various extrapulmonary sites. In addition to pulmonary symptoms, tuberculosis can also manifest outside the lungs. The ocular involvement of tuberculosis, often presenting as primary tuberculous chorioretinitis (PTCR), poses a significant diagnostic challenge for healthcare professionals. This review article sheds light on the intricate nature of diagnosing tuberculous infectious diseases in Bangladesh, highlighting the specific challenges faced in this setting. Despite commendable progress in tuberculosis control in Bangladesh, the advanced diagnosis of tuberculosis, particularly when it involves the eyes, presents formidable obstacles. This is especially true in cases of primary tuberculous chorioretinitis, which can pose a grave threat to vision and lead to life-threatening conditions, particularly in resource-poor settings. The article underscores the necessity for innovative and improvised diagnostic approaches to address the unique nature of these cases. Furthermore, the article delves into the implications of Mycobacterium tuberculosis infection in the eye, emphasizing its potential to cause severe blindness. To mitigate bias and enhance patient outcomes, the healthcare community must focus on raising public awareness, improving diagnostic techniques, and ensuring adherence to regulatory standards. This multifaceted approach is essential to effectively combat the challenges posed by tuberculosis, particularly in cases involving ocular manifestations.