Effect of epidural analgesia on postpartum bladder sensation

IF 1.9 4区 医学 Q2 OBSTETRICS & GYNECOLOGY European journal of obstetrics, gynecology, and reproductive biology Pub Date : 2025-04-17 Epub Date: 2025-02-21 DOI:10.1016/j.ejogrb.2025.02.037
G. Linfield-Brown , V. Khullar , L. Cardozo
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Abstract

Introduction

This study investigates the effects of epidural analgesia on postpartum urinary bladder sensation. Urinary retention and inability to void are well known side effects of epidural analgesia but the causes are unknown. The incidence of postpartum hypotonic bladder injury is increased in women receiving epidural analgesia during labour. We hypothesise that long-acting local anaesthetics used in epidural analgesia can impair bladder sensation and can lead to an increased risk of asymptomatic overdistension.

Method

Primiparous women between 38–42 weeks gestation who had received epidural analgesia prior to being in labour were recruited. The women were catheterised prior to insertion of the epidural to obtain baseline bladder sensation measurements of first sensation to void and maximum bladder capacity from cystometry. Women who delivered by spontaneous vaginal delivery were followed up. Postnatally, cystometry was repeated until bladder sensation returned to within 10 % of the pre-delivery volumes, bladders were not filled beyond 600 ml.

Results

Sixty women were recruited prior to insertion of the epidural but only eighteen were studied postpartum as they had a spontaneous vaginal delivery. The mean time for cystometry values to return to pre-delivery levels was 6.6 h with a maximum duration of 8 h. The mean volume of urine produced before bladder sensation returned was 1054 ml.

Conclusion

Epidural analgesia delays the return of bladder sensation by up to 8-hours post-delivery. The volume of urine passed during this time can be as much as 1400 ml. Bladder catheterisation should be performed following epidural analgesia to minimise the possibility of bladder overdistension.
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硬膜外镇痛对产后膀胱感觉的影响
前言:探讨硬膜外镇痛对产后膀胱感觉的影响。尿潴留和无法排尿是众所周知的硬膜外镇痛的副作用,但其原因尚不清楚。分娩时接受硬膜外镇痛的妇女产后膀胱低渗损伤的发生率增加。我们假设,在硬膜外镇痛中使用长效局部麻醉剂会损害膀胱感觉,并可能导致无症状过度膨胀的风险增加。方法选取妊娠38 ~ 42周、分娩前接受硬膜外镇痛的产妇为研究对象。这些妇女在硬膜外插入前导尿,以获得基线膀胱感觉测量,第一感觉为空,膀胱容量最大。对自然阴道分娩的妇女进行了随访。分娩后,反复进行膀胱测量,直到膀胱感觉恢复到产前容量的10%以内,膀胱充盈不超过600毫升。结果在硬膜外插入前招募了60名妇女,但只有18名妇女在产后进行了自然阴道分娩。膀胱测量值恢复到分娩前水平的平均时间为6.6 h,最长持续时间为8 h。膀胱感觉恢复前的平均尿量为1054 ml。结论硬膜外镇痛可延迟分娩后8小时膀胱感觉的恢复。在此期间排尿量可达1400毫升。硬膜外镇痛后应进行膀胱导尿,以尽量减少膀胱过度膨胀的可能性。
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来源期刊
CiteScore
4.60
自引率
3.80%
发文量
898
审稿时长
8.3 weeks
期刊介绍: The European Journal of Obstetrics & Gynecology and Reproductive Biology is the leading general clinical journal covering the continent. It publishes peer reviewed original research articles, as well as a wide range of news, book reviews, biographical, historical and educational articles and a lively correspondence section. Fields covered include obstetrics, prenatal diagnosis, maternal-fetal medicine, perinatology, general gynecology, gynecologic oncology, uro-gynecology, reproductive medicine, infertility, reproductive endocrinology, sexual medicine and reproductive ethics. The European Journal of Obstetrics & Gynecology and Reproductive Biology provides a forum for scientific and clinical professional communication in obstetrics and gynecology throughout Europe and the world.
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