{"title":"Time is spine: critical updates for the intensivist.","authors":"Ryan Sandarage, Joseph Y Nashed, Eve C Tsai","doi":"10.1097/MCC.0000000000001245","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose of review: </strong>The concept of 'time is spine' emphasizes early or ultra-early surgical decompression within 24 or 12 h, respectively, after spinal cord injury (SCI) to maximize recovery. This review updates the latest findings on the timing of surgical decompression and hemodynamic management in acute SCI, focusing on neurological outcomes and complications.</p><p><strong>Recent findings: </strong>While early decompression may improve neurological outcomes, factors like injury severity, comorbidities, and system resources affect surgical timing. Recent studies question the benefits of ultra-early decompression, finding no significant improvement at 12 months, suggesting earlier analyses may have overstated its benefits. Current recommendations include tailoring decompression timing to individual cases, considering patient-specific and systemic factors. New techniques like spinal cord pressure monitoring, intraoperative ultrasound, and advanced imaging are advancing targeted intervention and hemodynamic management in SCI.</p><p><strong>Summary: </strong>The timing of spinal decompression and hemodynamic management may impact neurological function, however, because of the deficiencies of current studies, individualized, patient-tailored decision-making is critical. A multidisciplinary approach that considers injury severity and patient characteristics is essential for optimal management. Further research is required to refine the timing of surgical intervention and explore additional factors influencing recovery.</p>","PeriodicalId":10851,"journal":{"name":"Current Opinion in Critical Care","volume":" ","pages":"117-122"},"PeriodicalIF":3.5000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Opinion in Critical Care","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/MCC.0000000000001245","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/27 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"CRITICAL CARE MEDICINE","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose of review: The concept of 'time is spine' emphasizes early or ultra-early surgical decompression within 24 or 12 h, respectively, after spinal cord injury (SCI) to maximize recovery. This review updates the latest findings on the timing of surgical decompression and hemodynamic management in acute SCI, focusing on neurological outcomes and complications.
Recent findings: While early decompression may improve neurological outcomes, factors like injury severity, comorbidities, and system resources affect surgical timing. Recent studies question the benefits of ultra-early decompression, finding no significant improvement at 12 months, suggesting earlier analyses may have overstated its benefits. Current recommendations include tailoring decompression timing to individual cases, considering patient-specific and systemic factors. New techniques like spinal cord pressure monitoring, intraoperative ultrasound, and advanced imaging are advancing targeted intervention and hemodynamic management in SCI.
Summary: The timing of spinal decompression and hemodynamic management may impact neurological function, however, because of the deficiencies of current studies, individualized, patient-tailored decision-making is critical. A multidisciplinary approach that considers injury severity and patient characteristics is essential for optimal management. Further research is required to refine the timing of surgical intervention and explore additional factors influencing recovery.
期刊介绍:
Current Opinion in Critical Care delivers a broad-based perspective on the most recent and most exciting developments in critical care from across the world. Published bimonthly and featuring thirteen key topics – including the respiratory system, neuroscience, trauma and infectious diseases – the journal’s renowned team of guest editors ensure a balanced, expert assessment of the recently published literature in each respective field with insightful editorials and on-the-mark invited reviews.